Evidence map›Paper›PMID 32648544›Full record

ArticleeLife2020

Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor.

Nami Kitajima, Kenji Takikawa, Hiroshi Sekiya, Kaname Satoh, Daisuke Asanuma, Hirokazu Sakamoto, Shodai Takahashi, Kenjiro Hanaoka, Yasuteru Urano, Shigeyuki Namiki and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Review
  3. Direct energy consumption by inhibitory GABAFrontiers in neuroscience · 2026
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  8. Review
  9. Article
  10. Article
  11. The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Synthetic nanosensors for imaging neuromodulators.Journal of neuroscience methods · 2021
    Review
  20. Neurotropin alleviates rat osteocarcinoma pain via PIranian journal of basic medical sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Nami KitajimaDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0001-9838-832X
Kenji TakikawaDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroshi SekiyaDepartment of Physiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kaname SatohDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Daisuke AsanumaDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hirokazu SakamotoDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Shodai TakahashiGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Kenjiro HanaokaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-0797-4038
Yasuteru UranoGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Shigeyuki NamikiDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-1520-8261
Masamitsu IinoDepartment of Cellular and Molecular Pharmacology, Nihon University School of Medicine, Tokyo, Japan.ORCID 0000-0001-6426-4206
Kenzo HiroseDepartment of Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-8944-6513
The University of Tokyo · JPNihon University · JP

Funding

Japan Science and Technology Agency JPMJPR17P1Ministry of Education, Culture, Sports, Science, and Technology 17H04029Ministry of Education, Culture, Sports, Science, and Technology 17H04764Ministry of Education, Culture, Sports, Science, and Technology 17K08584Ministry of Education, Culture, Sports, Science, and Technology 18H04609Ministry of Education, Culture, Sports, Science, and Technology 18H04726Ministry of Education, Culture, Sports, Science, and Technology 18K14915Ministry of Education, Culture, Sports, Science, and Technology 19H05414Ministry of Education, Culture, Sports, Science, and Technology 19K16251Ministry of Education, Culture, Sports, Science, and Technology 19K22247Ministry of Education, Culture, Sports, Science, and Technology 25221304
6 · The paper itself

Abstract

Adenosine 5' triphosphate (ATP) is a ubiquitous extracellular signaling messenger. Here, we describe a method for in-vivo imaging of extracellular ATP with high spatiotemporal resolution. We prepared a comprehensive set of cysteine-substitution mutants of ATP-binding protein,

Indexed as

Adenosine TriphosphateAnimalsBrainFunctional NeuroimagingMaleMiceMice, Inbred C57BLOptical ImagingAdenosine TriphosphateATPATPOSbiochemistrychemical biologyextracellular signaling moleculefluorescent sensorin vivo imagingmouseneuroscience

Identifiers

PMID32648544
PMCPMC7398694
OpenAlexW3041954268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.