ReviewThe world journal of men's health2021
The Natural History of Peyronie's Disease.
Review in The world journal of men's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- The Immunological Microenvironment and the Emerging Role of Stem Cells Therapy in Peyronie's Disease: A Systematic Narrative Review.International journal of molecular sciences · 2023Pooled it
- Bridging fibrosis and function: an integrated mechanistic and therapeutic framework for Peyronie's disease and related erectile dysfunction.Sexual medicine · 2026Review
- Impact ofInternational journal of molecular sciences · 2026Article
- YouTube as a Reliable Source of Patient Education for Peyronie's Disease: A Quality Assessment Study.Cureus · 2026Article
- Clinical features and risk factors analysis of diabetes mellitus complicated with Peyronie's disease.Sexual medicine · 2026Article
- Erectile dysfunction and Peyronie's disease: from biologics to nanomedicine-enabled therapies.Sexual medicine · 2026Review
- Guideline of guidelines: Peyronie's disease.BJU international · 2026Review
- Article
- Local surgical trauma in the penile tunica albuginea of the rat: a new animal model of Peyronie's disease.Sexual medicine · 2025Article
- A novel autologous material for the surgical treatment of Peyronie's disease: the outer plate of the prepuce.Translational andrology and urology · 2025Article
- Intralesional and topical treatments for Peyronie's disease: a narrative review of current knowledge.Asian journal of andrology · 2025Review
- Multimodal treatments based on Tadalafil during acute phase of Peyronie's disease: experience at two referral academic centers.Irish journal of medical science · 2024Article
- The prevalence and topographic distribution of penile calcification in a large cohort: a retrospective cross-sectional study.International journal of impotence research · 2024Article
- Acute Phase Peyronie's Disease: Where Do We Stand?Cureus · 2024Review
- Clinical Presentation of Peyronie's Disease: A Retrospective Study of 564 Cases.Diagnostics (Basel, Switzerland) · 2024Article
- Long-term outcomes of extracorporeal shock wave therapy for acute Peyronie's disease: a 10-year retrospective analysis.International journal of impotence research · 2024Article
- Long-term experiences with high-energy shock wave therapy in the management chronic phase Peyronie's disease using two different electromagnetic lithotripters.World journal of urology · 2024Article
- Medical Treatment for Peyronie's Disease: Systematic Review and Network Bayesian Meta-Analysis.The world journal of men's health · 2024Article
- [Current treatment concepts for Peyronie's disease].Urologie (Heidelberg, Germany) · 2023Article
- Molecular Mechanisms and Risk Factors Related to the Pathogenesis of Peyronie's Disease.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peyronie's disease (PD), a fibrotic disorder of the tunica albuginea fully described in 1793 by French physician Francois de la Peyronie, is characterized by pain, plaque formation, penile deformity, and ultimately sexual function decline. The epidemiological data on PD vary considerably across previous studies, with recent evidence reporting a prevalence of up to 9%. PD is generally divided into two different phases: active or acute and stable or chronic. Plaque formation generally occurs during the acute phase, while during chronic phase pain usually tends to complete resolution and penile deformity stabilizes. PD's pathophysiology is still subject of great discussion. Tunical mechanical stress and microvascular trauma are major contributory factors. However, better understanding of the molecular pathophysiology of this condition remains paramount towards an in-depth comprehension of the disorder and the development of newer and more effective disease-targeted interventions. In this review we provide a detailed overview of natural history of PD, specifically focusing on clinical manifestations and the underlying molecular regulation patterns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.