Evidence map›Paper›PMID 32648275›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Single-Molecule 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes.

Jin Lu, Hesam Mazidi, Tianben Ding, Oumeng Zhang, Matthew D Lew

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jin LuDepartment of Electrical and Systems Engineering, Center for Science and Engineering of Living Systems, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.ORCID 0000-0003-0905-0736
Hesam MazidiDepartment of Electrical and Systems Engineering, Center for Science and Engineering of Living Systems, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Tianben DingDepartment of Electrical and Systems Engineering, Center for Science and Engineering of Living Systems, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.ORCID 0000-0003-0710-2344
Oumeng ZhangDepartment of Electrical and Systems Engineering, Center for Science and Engineering of Living Systems, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.ORCID 0000-0001-7318-2130
Matthew D LewDepartment of Electrical and Systems Engineering, Center for Science and Engineering of Living Systems, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.ORCID 0000-0002-5614-3292

Funding

Six-Dimensional Single-Molecule Nanoscopy for Elucidating the Dynamic Organization of BiomoleculesR35GM124858 · NIGMS · WASHINGTON UNIVERSITY · PI Matthew D Lew · 2017 to 2026
$3.3M
HIGH PERFORMANCE BIOMEDICAL IMAGING COMPUTER RESOURCESS10RR022984 · NCRR · WASHINGTON UNIVERSITY · PI PRIOR, FRED WILLIAM · 2009 to 2009
$1.9M
GPU COMPUTING RESOURCE TO ENABLE INNOVATION IN IMAGING AND NETWORK BIOLOGYS10OD018091 · OD · WASHINGTON UNIVERSITY · PI PAPPU, ROHIT V, PRIOR, FRED WILLIAM · 2014 to 2014
$598k
NCRR NIH HHS S10 RR022984NIGMS NIH HHS R35 GM124858NIH HHS S10 OD018091
6 · The paper itself

Abstract

In soft matter, thermal energy causes molecules to continuously translate and rotate, even in crowded environments, thereby impacting the spatial organization and function of most molecular assemblies, such as lipid membranes. Directly measuring the orientation and spatial organization of large collections (>3000 molecules μm

Indexed as

Single Molecule ImagingFluorescent DyesLipid BilayersMembrane LipidsNanotechnologyOxazinesSphingomyelin PhosphodiesteraseFluorescent DyesLipid BilayersMembrane Lipidsnile redOxazinesSphingomyelin Phosphodiesteraselocalization microscopynanodomainsrotational diffusionsphingomyelinasesupported lipid bilayer

Identifiers

PMID32648275
PMCPMC7794097

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.