Evidence map›Paper›PMID 32648209›Full record

ReviewBiophysical reviews2020

Nanomolar ATP binding to single myosin cross-bridges in rigor: a molecular approach to studying myosin ATP kinetics using single human cardiomyocytes.

Elvis Pandzic, Christian A Morkel, Amy Li, Roger Cooke, Renee M Whan, Cristobal G Dos Remedios

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biophysical reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elvis PandzicBiomedical Imaging Facility, Mark Wainwright Analytical Centre, University of New South Wales, Kensington, 2052, Australia. e.pandzic@unsw.edu.au.ORCID http://orcid.org/0000-0003-3733-0890
Christian A MorkelVictor Chang Cardiac Research Institute, Molecular Cardiology Group, Darlinghurst, NSW, 2020, Australia.
Amy LiDepartment of Pharmacy & Biomedical Sciences, La Trobe University, Bendigo, 3552, Australia.
Roger CookeDepartment of Biochemistry, University of California, San Francisco, CA, 94158, USA.
Renee M WhanBiomedical Imaging Facility, Mark Wainwright Analytical Centre, University of New South Wales, Kensington, 2052, Australia.
Cristobal G Dos RemediosVictor Chang Cardiac Research Institute, Molecular Cardiology Group, Darlinghurst, NSW, 2020, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our knowledge in the field of cardiac muscle and associated cardiomyopathies has been evolving incrementally over the past 60 years and all was possible due to the parallel progress in techniques and methods allowing to take a fresh glimpse at an old problem. Here, we describe an exciting tool used to examine the various states of the human cardiac myosin at the single molecule level. By imaging single Alexa

Indexed as

ATP analoguesATP-binding kineticsHuman heart cardiomyocytesSingle molecule imaging of ATPSMLMTIRF microscopy

Identifiers

PMID32648209
PMCPMC7429591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.