Evidence map›Paper›PMID 32648140›Full record

ArticleTechniques in coloproctology2020

Injection of freshly collected autologous adipose tissue into non-healing wounds after closed incision pilonidal surgery.

S Haas, M J Sørensen, L Lundby, A G Pedersen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05830734 (Examining the Effect of Additional Injection of Freshly Collected Autologous Adipose Tissue to Bascom's Cleft Lift Surgery in the Treatment of Pilonidal Disease- a Randomized Controlled Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05830734 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Examining the Effect of Additional Injection of Freshly Collected Autologous Adipose Tissue to Bascom's Cleft Lift Surgery in the Treatment of Pilonidal Disease- a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of AarhusRan2023 to 2026Enrolled140ConditionsPilonidal DiseaseArmsinjection of freshly collected adipose cells, Bascoms Cleft lift procedure
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S HaasDepartment of Surgery, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark. Susahaas@rm.dk.ORCID 0000-0002-2135-433X
M J SørensenDepartment of Surgery, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark.
L LundbyDepartment of Surgery, Aarhus University Hospital, Aarhus, Denmark.
A G PedersenDepartment of Surgery, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark.
Regional Hospital Randers · DKAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic non-healing wounds are a major problem after closed incision pilonidal surgery. Freshly collected autologous adipose tissue injected into perianal fistulas in patients with Crohn's disease seems to promote healing. We investigated this technique in patients with non-healing wounds after cleft-lift surgery for pilonidal sinus disease (PSD).

methodIn a prospective interventional pilot study conducted at our institution autologous adipose tissue from the abdominal wall was harvested, and injected into chronic non-healing PS wounds after surgical revision, healing rate being the primary outcome. The wounds were left open. Patients were followed every 2 to 3 weeks until complete healing (skin coverage, no undermining).

results7 male patients were included (mean age 24 ± 0,6 SD years) and complete healing was achieved in 6 patients (86%). Median time to healing was 90 days (range 36-403 days ) and mean follow-up time was 388± 45 days. All patients reported major symptom relief shortly after the procedure. The mean operation time was 80 ± 23 minutes and the mean amount of freshly collected adipose tissue injected was 27.4± 12 ml. There were no complications.

conclusionsFreshly collected autologous adipose tissue injected into chronic non-healing pilonidal wounds seems safe and efficient.

Indexed as

Pilonidal SinusAdipose TissueAdultHumansMalePilot ProjectsProspective StudiesTreatment OutcomeYoung AdultAdipose tissue derived stem cellsAutologous fat injectionAutologous stem cellsNon-healing woundPilonidal diseaseRecurrent pilonidal disease

Identifiers

PMID32648140
OpenAlexW3042080551

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.