Evidence map›Paper›PMID 32648060›Full record

ArticleEnvironmental geochemistry and health2021

Geochemical compositional controls on DNA strand breaks induced in in vitro cell-free assays by crushed rock powders from the Panasqueira mine area, Portugal.

Hatim Badri, David A Polya, Andrew C Povey

Open access · hybridAbstract read
In one paragraph

Article in Environmental geochemistry and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Hatim BadriDepartment of Earth and Environmental Sciences and Williamson Research Centre for Molecular Environmental Science, University of Manchester, Williamson Building, Oxford Road, Manchester, M13 9PL, UK.
David A PolyaDepartment of Earth and Environmental Sciences and Williamson Research Centre for Molecular Environmental Science, University of Manchester, Williamson Building, Oxford Road, Manchester, M13 9PL, UK. david.polya@manchester.ac.uk.ORCID http://orcid.org/0000-0002-7484-6696
Andrew C PoveyDivision of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, M13 9PL, UK.
Manchester Academic Health Science Centre · GBUmm al-Qura University · SAUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA strand breaks are a common form of DNA damage that can contribute to chromosomal instability or gene mutations. Such strand breaks may be caused by exposure to heavy metals. The aim of this study was to assess the level of DNA strand breaks caused by µm-scale solid particles of known chemical composition with elevated heavy metals/metalloids, notably arsenic, using an in vitro cell-free DNA plasmid scission assay. These samples were incubated with and without H

Indexed as

ArsenicDNADNA DamageHydrogen PeroxideMetalloidsMetals, HeavyMineralsPortugalPowdersReactive Oxygen SpeciesArsenicDNAHydrogen PeroxideMetalloidsMetals, HeavyMineralsPowdersReactive Oxygen SpeciesCell-free assayDNA strand breaksHeavy metalsPanasqueiraParticlesToxicity

Identifiers

PMID32648060
PMCPMC8275547
OpenAlexW3041913113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.