Evidence map›Paper›PMID 32647943›Full record

ArticleMikrochimica acta2020

"Plug and Play" logic gate construction based on chemically triggered fluorescence switching of gold nanoparticles conjugated with Cy3-tagged aptamer.

Yali Zhang, Cheuk-Wing Li, Lefei Zhou, Zhanpeng Chen, Changqing Yi

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Logic Gates Based on DNA Aptamers.Pharmaceuticals (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yali ZhangKey Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, 510006, China.
Cheuk-Wing LiSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK.
Lefei ZhouKey Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, 510006, China.
Zhanpeng ChenKey Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, 510006, China.
Changqing YiKey Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, 510006, China. yichq@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0001-5477-902X
Sun Yat-sen University · CNNottingham Trent University · GB

Funding

Guangzhou Municipal Science and Technology Project 201803020026Natural Science Foundation of Guangdong Province S2017A030313076Shenzhen Technical Project JCYJ20170307140752183
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) conjugated with Cy3-tagged aptamer which can specifically recognize chloramphenicol (CAP) (referred to as AuNPs-AptCAP) are described. CAP can trigger the configuration change of CAP binding aptamer, and thus switching the fluorescence of AuNPs-AptCAP through changing the efficiency of the fluorescence resonance energy transfer (FRET) system with Cy3 as donors and AuNPs as recipients. AuNPs-AptCAP exhibits a linear range of CAP concentrations from 26.0 to 277 μg L

Indexed as

LogicAptamers, NucleotideBase SequenceCarbocyaninesChloramphenicolDNAEdetic AcidFluorescenceFluorescence Resonance Energy TransferFluorescent DyesGoldImmobilized Nucleic AcidsLimit of DetectionMercuryMetal NanoparticlesNickelAptamers, NucleotideCarbocyaninesChloramphenicolcyanine dye 3DNAEdetic AcidFluorescent DyesGoldImmobilized Nucleic AcidsMercuryNickelAptamerChloramphenicolFluorescence resonance energy transferGold nanoparticlesMolecular logic gate

Identifiers

PMID32647943
OpenAlexW3041587679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.