ReviewAnnals of translational medicine2020
Assessment of sublingual microcirculation in critically ill patients: consensus and debate.
Review in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Observational Pilot Study for the Multi-Modality Risk Prediction and Early Identification of Critically Ill Septic Patients in the Emergency Department
Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis.Systematic reviews · 2023Pooled it
- Sublingual microcirculatory assessment on admission independently predicts the outcome of old intensive care patients suffering from shock.Scientific reports · 2024Trial
- Direct assessment of microcirculation in shock: a randomized-controlled multicenter study.Intensive care medicine · 2023Trial
- Assessment of the Microcirculation During Extracorporeal Blood Purification in Septic Patients: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Microcirculatory perfusion is improved with plasma, but not with crystalloids, in a rat polytraumatic shock model.Transfusion · 2026Article
- Microcirculatory impairment and increased arterial stiffness in pediatric Long COVID patients.European journal of pediatrics · 2026Article
- Tissue Perfusion and Fluid Responsiveness Assessment in Critically Ill Patients. A Feasibility Pilot Study Using the Ikorus Urothelial Plethysmography Device (The Target-Up Study).Shock (Augusta, Ga.) · 2026Article
- Bedside measurement of microcirculation in critically ill patients: A scoping review protocol.PloS one · 2026Article
- Retinal Perfusion and Injury in Sepsis and after Major Surgery.Ophthalmology science · 2026Article
- Alterations of Sublingual Microcirculation in Children With Compensated Type 1 Diabetes Mellitus-An Observational Study.Pediatric diabetes · 2025Observational
- The microcirculation in the first days of ICU admission in critically ill COVID-19 patients is influenced by severity of disease.Scientific reports · 2024Article
- Changes of Sublingual Microcirculation during the Treatment of Severe Diabetic Ketoacidosis.Journal of clinical medicine · 2024Article
- Occult hypoperfusion and changes of systemic lipid levels after severe trauma: an analysis in a standardized porcine polytrauma model.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Treatment of patients with multiple organ dysfunction syndrome (MODS) with an electromagnetic field coupled to biorhythmically defined impulse configuration: the MicrocircMODS study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Therapeutic Effects of Shenfu Injection in Shock.Chinese journal of integrative medicine · 2023Review
- Association between diastolic blood pressure during the first 24 h and 28-day mortality in patients with septic shock: a retrospective observational study.European journal of medical research · 2023Observational
- Sepsis: network pathophysiology and implications for early diagnosis.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Review
- Multi-Omics Endotypes in ICU Sepsis-Induced Immunosuppression.Microorganisms · 2023Review
- Deep learning and computer vision techniques for microcirculation analysis: A review.Patterns (New York, N.Y.) · 2023Review
- End organ perfusion and pediatric microcirculation assessment.Frontiers in pediatrics · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main concern in shock and resuscitation is whether the microcirculation can carry adequate oxygen to the tissues and remove waste. Identification of an intact coherence between macro- and microcirculation during states of shock and resuscitation shows a functioning regulatory mechanism. However, loss of hemodynamic coherence between the macro and microcirculation can be encountered frequently in sepsis, cardiogenic shock, or any hemodynamically compromised patient. This loss of hemodynamic coherence results in an improvement in macrohemodynamic parameters following resuscitation without a parallel improvement in microcirculation resulting in tissue hypoxia and tissue compromise. Hand-held vital microscopes (HVMs) can visualize the microcirculation and help to diagnose the nature of microcirculatory shock. Although treatment with the sole aim of recruiting the microcirculation is as yet not realized, interventions can be tailored to the needs of the patient while monitoring sublingual microcirculation. With the help of the newly introduced software, called MicroTools, we believe sublingual microcirculation monitoring and diagnosis will be an essential point-of-care tool in managing shock patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.