ReviewAnnals of translational medicine2020
A narrative review of heart rate and variability in sepsis.
Review in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Heart Rate Variability Integrated into a Longitudinal Multimodal Model to Predict Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.Bioengineering (Basel, Switzerland) · 2026Article
- Ultra Short Heart Rate Variability as a Prognostic Marker in Pulmonary Embolism: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Analysis of heart rate variability in critical septic patients using a smartphone application: a prospective cohort study.Frontiers in medicine · 2026Article
- Detection of Nociceptive Stimuli Using the Newborn Infant Parasympathetic Evaluation Index in Children Aged From 3 to 18 Years.Paediatric anaesthesia · 2025Article
- Establishing normative values for short-term heart rate variability indices in healthy infants in the emergency department.Annals of translational medicine · 2025Article
- Lipopolysaccharide induced systemic inflammation and heart rate variability in a term newborn piglet model.Pediatric research · 2025Article
- Parsimonious Waveform-derived Features consisting of Pulse Arrival Time and Heart Rate Variability Predicts the Onset of Septic Shock.Biomedical signal processing and control · 2024Article
- Article
- A time series driven model for early sepsis prediction based on transformer module.BMC medical research methodology · 2024Article
- Eleven years of experience in operating a pediatric rapid response system at a children's hospital in South Korea.Acute and critical care · 2023Article
- HIRA: Heart Rate Interval based Rapid Alert score to characterize autonomic dysfunction among patients with sepsis-related acute respiratory failure (ARF).Physiological measurement · 2023Article
- Adding heart rate n-variability (HRnV) to clinical assessment potentially improves prediction of serious bacterial infections in young febrile infants at the emergency department: a prospective observational study.Annals of translational medicine · 2023Article
- Prognostic implications of ultra-short heart rate variability indices in hospitalized patients with infective endocarditis.PloS one · 2023Article
- Prospective multicenter study of heart rate variability with ANI monitor as predictor of mortality in critically ill patients with COVID-19.Scientific reports · 2022Article
- Do paediatric early warning systems reduce mortality and critical deterioration events among children? A systematic review and meta-analysis.Resuscitation plus · 2022Review
- The potential therapeutic benefits of low frequency haemodynamic oscillations.The Journal of physiology · 2022Article
- Leveraging Continuous Vital Sign Measurements for Real-Time Assessment of Autonomic Nervous System Dysfunction After Brain Injury: A Narrative Review of Current and Future Applications.Neurocritical care · 2022Review
- Detection and Monitoring of Viral Infections via Wearable Devices and Biometric Data.Annual review of biomedical engineering · 2022Review
- Classification of Blood Volume Decompensation State via Machine Learning Analysis of Multi-Modal Wearable-Compatible Physiological Signals.Sensors (Basel, Switzerland) · 2022Article
- Diagnosis of Neonatal Sepsis: The Role of Inflammatory Markers.Frontiers in pediatrics · 2022Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinicians face challenges in the timely diagnosis and management of pediatric sepsis. Pediatric heart rate has been incorporated into early warning systems and studied as a predictor for critical illness. We aim to review: (I) the role of heart rate in pediatric warning systems and (II) the role of heart rate variability (HRV) in adult and neonatal sepsis, with a focus on its potential applications in pediatrics. We conducted a literature search for papers published up to December 2019 on the utility of heart rate and HRV analysis in the diagnosis and management of sepsis, using four medical databases: PubMed, Google Scholar, EMBASE and Web of Science. This review demonstrates that the clinical utility of pediatric heart rate in predicting clinical deterioration is limited by the lack of consensus among warning systems, consensus-based guidelines, and evidence-based studies as to what constitutes abnormal heart rate in the pediatric age group. Current studies demonstrate that abnormal heart rate itself does not adequately discriminate children with sepsis from those without. HRV analysis provides a quick and non-invasive method of assessment and can provide more information than traditional heart rate. HRV analysis has the potential to add value in identification and prognostication of adult and neonatal sepsis. With further studies to explore its role, HRV analysis has the potential to add to current tools in the diagnosis and prognosis of pediatric sepsis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.