Evidence map›Paper›PMID 32647006›Full record

ArticleThe Journal of biological chemistry2020

A kinase cascade on the yeast lysosomal vacuole regulates its membrane dynamics: conserved kinase Env7 is phosphorylated by casein kinase Yck3.

Surya P Manandhar, Ikha M Siddiqah, Stephanie M Cocca, Editte Gharakhanian

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Surya P ManandharDepartment of Biological Sciences, California State University at Long Beach, Long Beach, California, USA.
Ikha M SiddiqahDepartment of Biological Sciences, California State University at Long Beach, Long Beach, California, USA.
Stephanie M CoccaDepartment of Biological Sciences, California State University at Long Beach, Long Beach, California, USA.
Editte GharakhanianDepartment of Biological Sciences, California State University at Long Beach, Long Beach, California, USA. Electronic address: e.ghara@csulb.edu.
California State University, Long Beach · US

Funding

Env7 as a Conserved Member of a Novel Kinase Cascade Regulating Membrane FusionSC1GM112560 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI GHARAKHANIAN, EDITTE · 2015 to 2018
$1.5M
NIGMS NIH HHS SC1 GM112560
6 · The paper itself

Abstract

Membrane fusion/fission is a highly dynamic and conserved process that responds to intra- and extracellular signals. Whereas the molecular machineries involved in membrane fusion/fission have been dissected, regulation of membrane dynamics remains poorly understood. The lysosomal vacuole of budding yeast (

Indexed as

Amino Acid MotifsCasein Kinase IIntracellular MembranesLysosomesMembrane FusionProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionVacuolesCasein Kinase IEnv7 protein, S cerevisiaeProtein Serine-Threonine KinasesSaccharomyces cerevisiae ProteinsYCK3 protein, S cerevisiaeCK1 Yck3Env7lysosomal vacuolelysosomemembrane fusionprotein phosphorylationregulation of membrane dynamicsSaccharomyces cerevisiaeserine/threonine protein kinasesubcellular organellevacuolar membrane dynamicsvacuole

Identifiers

PMID32647006
PMCPMC7443493
OpenAlexW3041579279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.