ArticleThe European respiratory journal2020
The associations of interstitial lung abnormalities with cancer diagnoses and mortality.
Registry-linked trialOpen access · bronzeAbstract read
In one paragraph
Article in The European respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05986318 (Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease: A 2x2 Factorial Randomized Phase II Trial Testing N-Acetyl Cysteine and Dexamethasone
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Clinical outcomes of interstitial lung abnormalities: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Prevalence, Risk Factors, and Outcomes of Adult Interstitial Lung Abnormalities: A Systematic Review and Meta-Analysis.American journal of respiratory and critical care medicine · 2023Pooled it
- Interstitial lung abnormalities in a large clinical lung cancer screening cohort: association with mortality and ILD diagnosis.Respiratory research · 2023Trial
- CT quantification of interstitial lung abnormalities: a prospective comparison between supine and prone positions.European radiology · 2026Article
- Automated quantification of interstitial lung abnormalities and emphysema on computed tomography: a predictive marker for postoperative pulmonary complications after esophagectomy.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Unsupervised risk factor identification across cancer types and data modalities via explainable artificial intelligence.NPJ digital medicine · 2026Article
- Incidental pulmonary findings on CT in daily practice: the nodule and the interstitial lung abnormalities - what's old, what's new.La Radiologia medica · 2026Review
- Interstitial lung abnormalities: a mechanistic window into early fibrotic lung disease.Frontiers in medicine · 2026Review
- Interstitial lung abnormality with preserved pulmonary function in lung cancer screening-eligible individuals: long-term effects on function and prognosis.European radiology · 2026Article
- Effect of contrast enhancement on diagnosis of interstitial lung abnormality in automatic quantitative CT measurement.European radiology · 2025Article
- Interactions between interstitial lung abnormalities and immune checkpoint inhibitor therapy in non-small cell lung cancer: A review of current understanding and future directions.Human vaccines & immunotherapeutics · 2025Review
- Quantitative Computed Tomography Measures of Lung Fibrosis and Outcomes in the National Lung Screening Trial.Annals of the American Thoracic Society · 2025Article
- Prognostic impacts of interstitial lung abnormalities on outcomes following resection for lung cancer.BMJ open respiratory research · 2025Article
- Analysis of baseline interstitial lung abnormality on the risk of checkpoint inhibitor-related pneumonitis and survival in advanced non-small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors.Translational lung cancer research · 2025Article
- Interstitial Lung Abnormalities: Unraveling the Journey from Incidental Discovery to Clinical Significance.Diagnostics (Basel, Switzerland) · 2025Review
- Predictive factors of fibrotic interstitial lung abnormality on high-resolution computed tomography scans: a prospective observational study.BMC pulmonary medicine · 2025Observational
- The role and machine learning analysis of mitochondrial autophagy-related gene expression in lung adenocarcinoma.Frontiers in immunology · 2025Article
- First-line chemoimmunotherapy for patients with small-cell lung cancer and interstitial lung abnormality: CIP risk and prognostic analysis.Thoracic cancer · 2024Article
- Postoperative pulmonary function of patients with lung cancer and interstitial lung abnormalities.General thoracic and cardiovascular surgery · 2024Article
- Long-Term Follow-Up of Interstitial Lung Abnormalities in Low-Dose Chest CT in Health Screening: Exploring the Predictors of Clinically Significant Interstitial Lung Diseases Using Artificial Intelligence-Based Quantitative CT Analysis.Journal of the Korean Society of Radiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Gisli T AxelssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland gtha7@hi.is.
Rachel K PutmanPulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Thor AspelundFaculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0002-7998-5433
Elias F GudmundssonIcelandic Heart Association, Kopavogur, Iceland.ORCID 0000-0002-7661-4872
Tomayuki HidaDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Tetsuro ArakiDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0440-6078
Mizuki NishinoDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Hiroto HatabuDept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1436-2988
Vilmundur GudnasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Gary M HunninghakePulmonary and Critical Care Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Gunnar GudmundssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Brigham and Women's Hospital · USUniversity of Iceland · ISIcelandic Heart Association · ISReykjavík University · IS
Funding
Clinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0MGenetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung AbnormalitiesR01HL135142 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL H. CHO, GARY MATTHEW HUNNINGHAKE · 2017 to 2026
$7.7MInterstitial Lung Abnormalities: Defining the Phenotype, Causes, and Consequences.R01HL111024 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HUNNINGHAKE, GARY MATTHEW · 2013 to 2022
$6.4MAutomated in vivo analysis of tumor growth rate as a guide for therapeutic decisions to advance personalized cancer treatmentR01CA203636 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI NISHINO, MIZUKI · 2017 to 2021
$2.9MProgression of interstitial lung abnormalities: the role of imaging and telomere length regulationK08HL140087 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI PUTMAN, RACHEL · 2018 to 2022
$852kNCI NIH HHS R01 CA203636NHLBI NIH HHS K08 HL140087NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL135142
Abstract
An increased incidence of lung cancer is well known among patients with idiopathic pulmonary fibrosis. It is not known whether interstitial lung abnormalities,
Indexed as
Lung NeoplasmsAdultEarly Detection of CancerHumansIcelandLungProportional Hazards ModelsTomography, X-Ray Computed
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
NCT05986318ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.