ArticleJACC. Cardiovascular interventions2020
Prognostic Impact of Race in Patients Undergoing PCI: Analysis From 10 Randomized Coronary Stent Trials.
Article in JACC. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 81 citations in OpenAlex.
- Paclitaxel-Coated Balloon for Treating In-Stent Restenosis in Racial and Ethnic Minority Patients: A Subanalysis From the AGENT IDE Trial.Journal of the American Heart Association · 2026Trial
- How Sex and Race/Ethnicity Influence Interventional Cardiology Outcomes: What Do We Know?Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- Equity at the Intersection of Heart Failure and Interventions: A Review of the Spectrum From Ambulatory Care to Cardiogenic Shock.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- Impact of Race and Ethnicity on Outcomes After Mitral Transcatheter Edge-to-Edge Repair: Analysis From the COAPT Trial.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel-Treated Participants.Clinical pharmacology and therapeutics · 2026Article
- Sex Differences in Polyvascular Disease - Implications for Lipid-Lowering Management and Cardiovascular Outcomes.Circulation reports · 2025Article
- Temporal Trends and Practice Patterns Associated With Utilization of Catheter-Based Interventions for Pulmonary Embolism.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Racial Disparities in Outcomes of Delivery and Cardiac Complications Among Pregnant Women with Congenital Heart Disease.Journal of racial and ethnic health disparities · 2025Article
- Advancing Health Equity in the Cardiovascular Device Life Cycle.Circulation. Cardiovascular quality and outcomes · 2025Review
- Population-Level Gaps in Coronary Artery Disease Care: A Focused Review.Methodist DeBakey cardiovascular journal · 2025Review
- Clinical Trial Diversity, Equity, and Inclusion: Roadmap of the Cardiothoracic Surgical Trials Network.The Annals of thoracic surgery · 2024Review
- Ethnic minorities treated with new-generation drug-eluting coronary stents in two European randomised clinical trials.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Article
- Cardiac interventions on total knee arthroplasty: a national inpatient sample-based analysis.Archives of orthopaedic and trauma surgery · 2024Article
- Paclitaxel-eluting stents versus paclitaxel-coated balloons in coronary artery disease: a meta-analysis of randomized controlled trials.Global cardiology science & practice · 2024Review
- Racial/ethnic differences persist in treatment choice and outcomes in isolated intervention for coronary artery disease.The Journal of thoracic and cardiovascular surgery · 2023Article
- US Initiative to Eliminate Racial and Ethnic Disparities in Health: The Impact on the Outcomes of ST-Segment-Elevation Myocardial Infarction in New Jersey.Journal of the American Heart Association · 2023Article
- Evaluation of Potential Racial Disparities in CYP2C19-Guided P2YClinical pharmacology and therapeutics · 2023Article
- Appropriateness of Percutaneous Coronary Interventions: A Systematic Review and Meta-Analysis.Journal of cardiovascular development and disease · 2023Review
- Pharmacogenetics of P2YPharmacotherapy · 2023Review
- Interaction Between Race and Income on Cardiac Outcomes After Percutaneous Coronary Intervention.Journal of the American Heart Association · 2022Article
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Authors and funding
11 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to assess race-based differences in patients undergoing percutaneous coronary intervention from a large pooled database of randomized controlled trials.
backgroundData on race-based outcomes after percutaneous coronary intervention are limited, deriving mainly from registries and single-center studies.
methodsBaseline characteristics and outcomes at 30 days, 1 year, and 5 years were assessed across different races, from an individual patient data pooled analysis from 10 randomized trials. Endpoints of interest included death, myocardial infarction, and major adverse cardiac events (defined as cardiac death, myocardial infarction, or ischemia-driven target lesion revascularization). Multivariate Cox proportional hazards regression was performed to assess associations between race and outcomes, controlling for differences in 12 baseline covariates.
resultsAmong 22,638 patients, 20,585 (90.9%) were white, 918 (4.1%) were black, 404 (1.8%) were Asian, and 473 (2.1%) were Hispanic. Baseline and angiographic characteristics differed among groups. Five-year major adverse cardiac event rates were 18.8% in white patients (reference group), compared with 23.9% in black patients (p = 0.0009), 11.2% in Asian patients (p = 0.0007), and 21.5% in Hispanic patients (p = 0.07). Multivariate analysis demonstrated an independent association between black race and 5-year risk for major adverse cardiac events (hazard ratio: 1.28; 95% confidence interval: 1.05 to 1.57; p = 0.01).
conclusionsIn the present large-scale individual patient data pooled analysis, comorbidities were significantly more frequent in minority-group patients than in white patients enrolled in coronary stent randomized controlled trials. After accounting for these differences, black race was an independent predictor of worse outcomes, whereas Hispanic ethnicity and Asian race were not. Further research examining race-based outcomes after percutaneous coronary intervention is warranted to understand these differences.
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