Evidence map›Paper›PMID 32646453›Full record

Observational studyBMC musculoskeletal disorders2020

No differences in cost-effectiveness and short-term functional outcomes between cemented and uncemented total knee arthroplasty.

R Rassir, P A Nolte, J C T van der Lugt, R G H H Nelissen, I N Sierevelt, W C Verra

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R RassirDepartment of Orthopaedic Surgery, Spaarne Hospital, Spaarnepoort 1, 2134, TM, Hoofddorp, the Netherlands. rrassir@spaarnegasthuis.nl.ORCID http://orcid.org/0000-0001-8417-6617
P A NolteDepartment of Orthopaedic Surgery, Spaarne Hospital, Spaarnepoort 1, 2134, TM, Hoofddorp, the Netherlands.
J C T van der LugtDepartment of Orthopaedic Surgery, Haga Hospital, The Hague, the Netherlands.
R G H H NelissenDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands.
I N SiereveltSpaarne Academy, Department of Epidemiology, Spaarne Hospital, Hoofddorp, the Netherlands.
W C VerraDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is an ongoing debate regarding optimal fixation of total knee arthroplasty (TKA), however cost has not been addressed as profoundly. Therefore, the current study primarily aimed to compare costs and cost-effectiveness 1 year after cemented or uncemented TKA. A secondary objective was to compare short-term functional outcomes between both groups.

methodsA posthoc prospective observational multicenter cohort study of 60 cemented and 50 uncemented Low Contact Stress (LCS) knee systems. Outcome was evaluated using the EuroQol5D-3 L (EQ5D) index, in order to calculate quality adjusted life years (QALYs). Total costs were calculated considering direct costs within the hospital setting (inpatient cost) as well as direct and indirect costs outside the hospital. Cost-effectiveness (total costs per QALY), Oxford Knee Score (OKS) and Numeric Rating Scale (NRS) were compared between cemented and uncemented cases at 1 year after surgery. HealthBASKET project, a micro-costing approach, represents the Dutch costs and situation and was used to calculate hospital stay. (In) direct costs outside the healthcare (medical cost and productivity cost) were determined using two validated questionnaires.

resultsMedian costs per QALY were similar between cemented and uncemented TKA patients (€16,269 and €17,727 respectively; p = 0.50). Median OKS (44 and 42; p = 0.79), EQ5D (0.88 and 0.90; p = 0.82) and NRS for pain (1.0 and 1.0; p = 0.48) and satisfaction (9.0 and 9.0; p = 0.15) were also comparable between both groups.

conclusionFor this type of knee implant (LCS), inpatient hospital costs and costs after hospitalization were comparable between groups.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisCohort StudiesCost-Benefit AnalysisHumansKnee JointCementedCost-effectivenessCostsQuality adjusted life yearsTotal knee ArthroplastyUncemented

Identifiers

PMID32646453
PMCPMC7350734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.