Evidence map›Paper›PMID 32646395›Full record

ArticleBMC musculoskeletal disorders2020

Impact of comorbidity on the short- and medium-term risk of revision in total hip and knee arthroplasty.

Jorge Arias-de la Torre, Kayla Smith, Alexandru Dregan, Jose M Valderas, Jonathan P Evans, Daniel Prieto-Alhambra, Luis Lozano, Antonio J Molina, Vicente Martín, Laia Domingo and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Joint-specific measures improve risk adjustment in total knee arthroplasty: A machine learning approach.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
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  6. Review
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  8. Article
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  14. Global mapping of institutional and hospital-based (Level II-IV) arthroplasty registries: a scoping review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Jorge Arias-de la TorreAgency for Heath Quality and Assessment of Catalonia (AQuAS), Carrer de Roc Boronat, 81, 08005, Barcelona, Spain. jorgeariasdelatorre@gmail.com.ORCID http://orcid.org/0000-0001-6908-9611
Kayla SmithAgency for Heath Quality and Assessment of Catalonia (AQuAS), Carrer de Roc Boronat, 81, 08005, Barcelona, Spain.
Alexandru DreganKing's College London, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, UK.
Jose M ValderasHealth Services and Policy Research Group, University of Exeter Medical School, Exeter, UK.
Jonathan P EvansHealth Services and Policy Research Group, University of Exeter Medical School, Exeter, UK.
Daniel Prieto-AlhambraOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Luis LozanoHospital Clinic de Barcelona, Barcelona, Spain.
Antonio J MolinaCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Vicente MartínCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Laia DomingoHealth Services Research on Chronic Patients Network (REDISSEC), Madrid, Spain.
Laura MuñozAgency for Heath Quality and Assessment of Catalonia (AQuAS), Carrer de Roc Boronat, 81, 08005, Barcelona, Spain.
Mireia EspallarguesAgency for Heath Quality and Assessment of Catalonia (AQuAS), Carrer de Roc Boronat, 81, 08005, Barcelona, Spain.
Spanish Clinical Research Network · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESKing's College London · GBUniversity of Exeter · GBHospital Clínic de Barcelona · ESUniversity of Oxford · GB

Funding

Instituto de Salud Carlos III CIBERESP 2017 & 2018
6 · The paper itself

Abstract

backgroundThe impact of comorbidity on the risk of revision in patients undergoing Total Knee arthroplasty (TKA) and Total Hip Arthroplasty (THA) is not currently well known. The aim of this study was to analyze the impact of comorbidity on the risk of revision in TKA and THA.

methodsPatients recorded in the Catalan Arthroplasty Register (RACat) between 01/01/2005 and 31/12/2016 undergoing TKA (n = 49,701) and THA (n = 17,923) caused by osteoarthritis were included. As main explanatory factors, comorbidity burden was assessed by the Elixhauser index, categorized, and specific comorbidities from the index were taken into account. Descriptive analyses for comorbidity burden and specific conditions were done. Additionally, incidence at 1 and 5 years' follow-up was calculated, and adjusted Competing Risks models were fitted.

resultsA higher incidence of revision was observed when the number of comorbidities was high, both at 1 and 5 years for THA, but only at 1 year for TKA. Of the specific conditions, only obesity was related to the incidence of revision at 1 year in both joints, and at 5 years in TKA. The risk of revision was related to deficiency anemia and liver diseases in TKA, while in THA, it was related to peripheral vascular disorders, metastatic cancer and psychoses.

conclusionsDifferent conditions, depending on the joint, might be related to higher revision rates. This information could be relevant for clinical decision-making, patient-specific information and improving the results of both TKA and THA.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeComorbidityHumansObesityReoperationRetrospective StudiesArthroplasty revisionComorbidityRegister studiesTotal hip arthroplastyTotal knee arthroplasty

Identifiers

PMID32646395
PMCPMC7346613
OpenAlexW3038128844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.