Evidence map›Paper›PMID 32645994›Full record

ReviewBiomolecules2020

Ten-Year Research Update Review: Antiviral Activities from Marine Organisms.

Gennaro Riccio, Nadia Ruocco, Mirko Mutalipassi, Maria Costantini, Valerio Zupo, Daniela Coppola, Donatella de Pascale, Chiara Lauritano

Abstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Marine AlgaMarine drugs · 2022
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gennaro RiccioMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.ORCID 0000-0003-2541-5790
Nadia RuoccoMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.
Mirko MutalipassiMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.ORCID 0000-0002-5521-5303
Maria CostantiniMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.
Valerio ZupoMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.ORCID 0000-0001-9766-8784
Daniela CoppolaMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.
Donatella de PascaleMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.
Chiara LauritanoMarine Biotechnology Department, Stazione Zoologica Anton Dohrn, CAP, 80121 Naples, Italy.ORCID 0000-0003-4580-9594

Funding

Progetto POR Campania PG/2018/0494374
6 · The paper itself

Abstract

Oceans cover more than 70 percent of the surface of our planet and are characterized by huge taxonomic and chemical diversity of marine organisms. Several studies have shown that marine organisms produce a variety of compounds, derived from primary or secondary metabolism, which may have antiviral activities. In particular, certain marine metabolites are active towards a plethora of viruses. Multiple mechanisms of action have been found, as well as different targets. This review gives an overview of the marine-derived compounds discovered in the last 10 years. Even if marine organisms produce a wide variety of different compounds, there is only one compound available on the market, Ara-A, and only another one is in phase I clinical trials, named Griffithsin. The recent pandemic emergency caused by SARS-CoV-2, also known as COVID-19, highlights the need to further invest in this field, in order to shed light on marine compound potentiality and discover new drugs from the sea.

Indexed as

Antiviral AgentsAquatic OrganismsBiological ProductsCoronaviridaeAntiviral AgentsBiological Productsantiviralmarine natural productsmarine organismsviruses

Identifiers

PMID32645994
PMCPMC7407529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.