Evidence map›Paper›PMID 32645980›Full record

ReviewNutrients2020

Dietary Strategies for Maintenance of Clinical Remission in Inflammatory Bowel Diseases: Are We There Yet?

Konstantinos Gkikas, Konstantinos Gerasimidis, Simon Milling, Umer Z Ijaz, Richard Hansen, Richard K Russell

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05606419 (The Crohn's Disease Exclusion Diet With Early Dairy Introduction vs Partial Enteral Nutrition), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05606419 nasuspendednot on this mapstarted 2024, after this paper: background citation

The Crohn's Disease Exclusion Diet With Early Dairy Introduction vs Partial Enteral Nutrition (CD-EDEN) in Adult Patients With Crohn's Disease

TypeinterventionalSponsorEvangelismos HospitalRan2024 to 2026Enrolled44ConditionsCrohn DiseaseArmsCDED+PEN, CDED+dairy
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Inflammatory bowel disease: recent developments.Archives of disease in childhood · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Feeding Difficulties Associated with IBD during the Working Day: Qualitative Study, Alicante Spain.International journal of environmental research and public health · 2022
    Article
  17. Observational
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Konstantinos GkikasHuman Nutrition, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UK.ORCID 0000-0003-1581-6566
Konstantinos GerasimidisHuman Nutrition, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UK.ORCID 0000-0001-9432-2200
Simon MillingInstitute for Infection, Immunity and Inflammation, University of Glasgow, Glasgow G12 8QQ, UK.
Umer Z IjazCivil Engineering, School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0001-5780-8551
Richard HansenDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow G51 4TF, UK.
Richard K RussellDepartment of Paediatric Gastroenterology, Royal Hospital for Sick Children, Edinburgh EH9 1LF, UK.ORCID 0000-0001-7398-4926
Glasgow Royal Infirmary · GBRoyal Hospital for Children · GBUniversity of Glasgow · GB

Funding

Nestle Health Science n/a
6 · The paper itself

Abstract

The etiopathogenesis of Inflammatory bowel disease (IBD) is a result of a complex interaction between host immune response, the gut microbiome and environmental factors, such as diet. Although scientific advances, with the use of biological medications, have revolutionized IBD treatment, the challenge for maintaining clinical remission and delaying clinical relapse is still present. As exclusive enteral nutrition has become a well-established treatment for the induction of remission in pediatric Crohn's disease, the scientific interest regarding diet in IBD is now focused on the development of follow-on dietary strategies, which aim to suppress colonic inflammation and delay a disease flare. The objective of this review is to present an extensive overview of the dietary strategies, which have been used in the literature to maintain clinical remission in both Crohn's disease and Ulcerative colitis, and the evidence surrounding the association of dietary components with clinical relapse. We also aim to provide study-related recommendations to be encompassed in future research studies aiming to investigate the role of diet during remission periods in IBD.

Indexed as

AdultChildColitis, UlcerativeCrohn DiseaseDietEnteral NutritionGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesRecurrenceRemission Inductionclinical relapseCrohn’s diseasedietary therapydietary triggersinflammatory bowel diseasemaintenance enteral nutritionUlcerative colitis

Identifiers

PMID32645980
PMCPMC7400838
OpenAlexW3039673745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.