Evidence map›Paper›PMID 32645934›Full record

Trial reportNutrients2020

Effects of Prolonged Whey Protein Supplementation and Resistance Training on Biomarkers of Vitamin B12 Status: A 1-Year Randomized Intervention in Healthy Older Adults (the CALM Study).

Eva Greibe, Søren Reitelseder, Rasmus L Bechshøft, Jacob Bülow, Grith W Højfeldt, Simon R Schacht, Mads L Knudsen, Inge Tetens, Marie S Ostenfeld, Ulla R Mikkelsen and 3 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Vitamin BJDS communications · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Eva GreibeDepartment of Clinical Medicine/Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200 Aarhus N, Denmark.ORCID 0000-0002-0417-1195
Søren ReitelsederInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital, Nielsine Nielsens Vej 11, DK-2400 Copenhagen NV, Denmark.
Rasmus L BechshøftInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital, Nielsine Nielsens Vej 11, DK-2400 Copenhagen NV, Denmark.
Jacob BülowInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital, Nielsine Nielsens Vej 11, DK-2400 Copenhagen NV, Denmark.
Grith W HøjfeldtInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital, Nielsine Nielsens Vej 11, DK-2400 Copenhagen NV, Denmark.
Simon R SchachtDepartment of Nutrition, Exercise, and Sports, University of Copenhagen, Noerre Alle 51, DK-2200 Copenhagen N, Denmark.
Mads L KnudsenDepartment of Nutrition, Exercise, and Sports, University of Copenhagen, Noerre Alle 51, DK-2200 Copenhagen N, Denmark.ORCID 0000-0002-4999-1218
Inge TetensDepartment of Nutrition, Exercise, and Sports, University of Copenhagen, Noerre Alle 51, DK-2200 Copenhagen N, Denmark.ORCID 0000-0002-2495-2511
Marie S OstenfeldArla Foods Ingredients Group P/S, Soenderhoej 10-12, DK-8260 Viby J, Denmark.
Ulla R MikkelsenArla Foods Ingredients Group P/S, Soenderhoej 10-12, DK-8260 Viby J, Denmark.
Christian W HeegaardDepartment of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10, DK-8000 Aarhus, Denmark.ORCID 0000-0002-7989-2624
Ebba NexoDepartment of Clinical Medicine/Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200 Aarhus N, Denmark.ORCID 0000-0001-9406-9081
Lars HolmInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital, Nielsine Nielsens Vej 11, DK-2400 Copenhagen NV, Denmark.
University of Copenhagen · DKAarhus University Hospital · DKArla Foods (Denmark) · DKAarhus University · DK

Funding

Innovationsfonden 12-132437Innovationsfonden 4096-00003B
6 · The paper itself

Abstract

We investigated the effect of long-term whey supplementation on biomarkers of B12 status in healthy older adults subjected to different schemes of supplements and exercise. The total study population examined at baseline consisted of 167 healthy older adults (age ≥ 65 year) who were randomized to 1-y intervention with two daily supplements of (1) whey protein (3.1 µg B12/day) (WHEY-ALL), (2) collagen (1.3 µg B12/day) (COLL), or (3) maltodextrin (0.3 µg B12/day) (CARB). WHEY-ALL was comprised of three groups, who performed heavy resistance training (HRTW), light resistance training (LITW), or no training (WHEY). Dietary intake was assessed through 3-d dietary records. For the longitudinal part of the study, we included only the participants (

Indexed as

Dietary SupplementsAgedAged, 80 and overBiomarkersCollagenDenmarkDietary CarbohydratesDiet RecordsExerciseFemaleHealthy VolunteersHumansMaleMethylmalonic AcidNutritional StatusPolysaccharidesBiomarkersCollagenDietary CarbohydratesmaltodextrinMethylmalonic AcidPolysaccharidesTranscobalaminsVitamin B 12Whey Proteinscarbohydratecobalamincollagencollagen protein hydrolysateexercisefasting versus non-fasting blood samplesinterventionmaltodextrinvitamin B12wheywhey protein hydrolysate

Identifiers

PMID32645934
PMCPMC7400943
OpenAlexW3039492289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.