Evidence map›Paper›PMID 32645912›Full record

ArticleMolecules (Basel, Switzerland)2020

New Paracyclophanylthiazoles with Anti-Leukemia Activity: Design, Synthesis, Molecular Docking, and Mechanistic Studies.

Ashraf A Aly, Stefan Bräse, Alaa A Hassan, Nasr K Mohamed, Lamiaa E Abd El-Haleem, Martin Nieger, Nesrin M Morsy, Elshimaa M N Abdelhafez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ashraf A AlyChemistry Department, Faculty of Science, Minia University, 61519-El-Minia, Egypt.ORCID 0000-0002-0314-3408
Stefan BräseInstitute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.
Alaa A HassanChemistry Department, Faculty of Science, Minia University, 61519-El-Minia, Egypt.
Nasr K MohamedChemistry Department, Faculty of Science, Minia University, 61519-El-Minia, Egypt.
Lamiaa E Abd El-HaleemChemistry Department, Faculty of Science, Minia University, 61519-El-Minia, Egypt.
Martin NiegerDepartment of Chemistry, University of Helsinki, P.O. Box 55 (A. I. Virtasen aukio I), 00014 Helsinki, Finland.
Nesrin M MorsyOrganometallic and Organometalloid Chemistry Department, National Research Centre, Dokki, 12622 Cairo, Egypt.ORCID 0000-0003-3636-1767
Elshimaa M N AbdelhafezDepartment of Medicinal Chemistry, Faculty of Pharmacy, Minia University, 61519-El Minia, Egypt.
Minia University · EGKarlsruhe Institute of Technology · DENational Research Centre · EGUniversity of Helsinki · FI

Funding

Karlsruhe Institute of Technology KIT-Publication Fund
6 · The paper itself

Abstract

A new series of methyl 2-(2-(4'-[2.2]paracyclophanyl)-hydrazinylidene)-3-substituted-4-oxothiazolidin-5-ylidene)acetates

Indexed as

Antineoplastic AgentsDrug DesignLeukemiaMolecular Docking SimulationThiazolesCell Line, TumorDrug Screening Assays, AntitumorHumansNeoplasm ProteinsAntineoplastic AgentsNeoplasm ProteinsThiazolescancer cell linesdockingmechanismNCI-60NMRparacyclophanesX-ray

Identifiers

PMID32645912
PMCPMC7411887
OpenAlexW3038827218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.