Evidence map›Paper›PMID 32645850›Full record

ArticleNutrients2020

Impaired Daytime Urinary Sodium Excretion Impacts Nighttime Blood Pressure and Nocturnal Dipping at Older Ages in the General Population.

Rosaria Del Giorno, Chiara Troiani, Sofia Gabutti, Kevyn Stefanelli, Sandro Puggelli, Luca Gabutti

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  5. Article
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  8. Article
  9. Article
  10. Current perspective on circadian function of the kidney.American journal of physiology. Renal physiology · 2024
    Review
  11. Article
  12. Seasonality in nighttime blood pressure and its associations with target organ damage.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  13. Review
  14. Circadian rhythms and renal pathophysiology.The Journal of clinical investigation · 2022
    Review
  15. Circadian Control of Sodium and Blood Pressure Regulation.American journal of hypertension · 2021
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Rosaria Del GiornoDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.ORCID 0000-0001-5206-8865
Chiara TroianiDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Sofia GabuttiDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Kevyn StefanelliDepartment of Social Sciences and Economics; Sapienza University of Rome, 00185 Rome, Italy.
Sandro PuggelliDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Luca GabuttiDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.ORCID 0000-0002-1929-6759
Ente Ospedaliero Cantonale · CHSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circadian rhythm of urinary sodium excretion is related to the diurnal blood pressure regulation (BP) and the nocturnal dipping pattern. The renal sodium excretion expressed as daytime/nighttime ratio impacts BP, but a limited number of studies have investigated this topic to date. In this cross-sectional study, we aimed to investigate the impact of different daily patterns of sodium excretion (comparing low with high ratios) on BP and nocturnal dipping and to explore the relationship with age. Twenty-four-hour ambulatory BP monitoring and daytime and nighttime urinary sodium collections were used to assess 1062 subjects in Switzerland. Analyses were performed according to the day/night urinary sodium excretion ratio quartiles (Q1-Q4) and by age group (≤50 and ≥50 years). Subjects in Q1 can be considered low excretors of sodium during the daytime since the rate of sodium excretion during the daytime was 40% lower than that of subjects in Q4. Quartiles of the day/night urinary sodium excretion ratio showed that subjects in Q1 were 7 years older and had respectively 6 and 5 mmHg higher nighttime systolic and diastolic BP and a higher nocturnal dipping compared with subjects in Q4 (

Indexed as

Blood PressureCircadian RhythmAdultAgedAge FactorsBlood Pressure Monitoring, AmbulatoryCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedPotassiumSodiumSwitzerlandPotassiumSodium24-h blood pressuredaytime urinary sodium excretionnighttime urinary sodium excretionnocturnal dippingurinary sodium excretion

Identifiers

PMID32645850
PMCPMC7400814
OpenAlexW3038810189

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.