Evidence map›Paper›PMID 32645834›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Potent and Specific Antibacterial Activity against

Nicolás Gómez-Sequeda, Jennifer Ruiz, Claudia Ortiz, Mauricio Urquiza, Rodrigo Torres

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

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  11. Effect of Essential Oil fromAntibiotics (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nicolás Gómez-SequedaGrupo de Investigación en Bioquímica y Microbiología (GIBIM), Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Jennifer RuizGrupo de Investigación en Bioquímica y Microbiología (GIBIM), Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Claudia OrtizGrupo de Investigación en Bioquímica y Microbiología (GIBIM), Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Mauricio UrquizaDepartamento de Química, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
Rodrigo TorresDepartamento de Ciencias Básicas, Facultad de Salud, Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Industrial University of Santander · COUniversidad Nacional de Colombia · CO

Funding

Departamento Administrativo de Ciencia, Tecnología e Innovación (Colciencias) and Universidad Industrial de Santander, Vicerrectoría de Investigación y Extensión 1102-6574-0828
6 · The paper itself

Abstract

Antimicrobial peptides constitute an excellent alternative against conventional antibiotics because of their potent antimicrobial spectrum, unspecific action mechanism and low capacity to produce antibiotic resistance. However, a potential use of these biological molecules as therapeutic agents is threatened by their low stability and susceptibility to proteases. In order to overcome these limitations, encapsulation in biocompatible polymers as poly-lactic-glycolic-acid (PLGA) is a promising alternative for increasing their stability and bioavailability. In this work, the effect of new synthetic antimicrobial peptides GIBIM-P5S9K (G17) and GAM019 (G19) encapsulated on PLGA and acting against methicillin resistant

Indexed as

antimicrobial peptidesE. coli O157:H7MRSAnanoencapsulation

Identifiers

PMID32645834
PMCPMC7400247
OpenAlexW3038404133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.