Evidence map›Paper›PMID 32645633›Full record

ReviewInternational immunopharmacology2020

An update on antiviral antibody-based biopharmaceuticals.

Shahrzad Ahangarzadeh, Zahra Payandeh, Roghaye Arezumand, Kiana Shahzamani, Fatemeh Yarian, Abbas Alibakhshi

Open access · greenAbstract readReview
In one paragraph

Review in International immunopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Vaginally-delivered fast-dissolving antibody tablets (FDAT) for on-demand non-hormonal contraception and multi-purpose protection.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Would New SARS-CoV-2 Variants Change the War against COVID-19?Epidemiologia (Basel, Switzerland) · 2022
    Article
  13. UsingExpert opinion on drug discovery · 2022
    Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Shahrzad AhangarzadehInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra PayandehImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Roghaye ArezumandDepartment of Medical Biotechnology and Molecular Science, North Khorasan University of Medical Science, Bojnurd, Iran.
Kiana ShahzamaniIsfahan Gastroenterology and Hepatology Research Center (IGHRC), Isfahan University of Medical Sciences, Isfahan, Iran.
Fatemeh YarianCellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: f.yarian@sbmu.ac.ir.
Abbas AlibakhshiDepartment of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: alibakhshi@sbmu.ac.ir.
Isfahan University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRNorth Khorasan University of Medical Sciences · IRTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the vastness of the science virology, it is no longer an offshoot solely of the microbiology. Viruses have become as the causative agents of major epidemics throughout history. Many therapeutic strategies have been used for these microorganisms, and in this way the recognizing of potential targets of viruses is of particular importance for success. For decades, antibodies and antibody fragments have occupied a significant body of the treatment approaches against infectious diseases. Because of their high affinity, they can be designed and engineered against a variety of purposes, mainly since antibody fragments such as scFv, nanobody, diabody, and bispecific antibody have emerged owing to their small size and interesting properties. In this review, we have discussed the antibody discovery and molecular and biological design of antibody fragments as inspiring therapeutic and diagnostic agents against viral targets.

Indexed as

AnimalsAntibodies, BispecificAntibodies, MonoclonalAntibodies, ViralBetacoronavirusBiological ProductsCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentDisease Models, AnimalDrug DesignDrug DiscoveryHumansPandemicsPneumonia, ViralSARS-CoV-2Antibodies, BispecificAntibodies, MonoclonalAntibodies, ViralBiological ProductsSingle-Domain AntibodiesAntibody fragmentsBiopharmaceuticalsCovid-19Monoclonal antibodyViral infectionsViral targets

Identifiers

PMID32645633
PMCPMC7336121
OpenAlexW3041959031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.