Evidence map›Paper›PMID 32645361›Full record

ArticleJournal of hepatology2020

Inflammasome activation and pyroptosis in lymphopenic liver patients with COVID-19.

Alexander Kroemer, Khalid Khan, Matthew Plassmeyer, Oral Alpan, M A Haseeb, Raavi Gupta, Thomas M Fishbein

Abstract readLetterComment
In one paragraph

Article in Journal of hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  6. Review
  7. Article
  8. The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Article
  9. Article
  10. Article
  11. Role of senescence in the chronic health consequences of COVID-19.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Acquiring high expression of suilysin enable non-epidemicEmerging microbes & infections · 2021
    Article
  17. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Alexander KroemerMedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center. Electronic address: alexander.h.kroemer@gunet.georgetown.edu.
Khalid KhanMedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center.
Matthew PlassmeyerSection on Immunopathogenesis, Amerimmune.
Oral AlpanSection on Immunopathogenesis, Amerimmune.
M A HaseebSUNY Downstate Health Sciences University, Departments of Pathology and Cell Biology, Brooklyn, New York.
Raavi GuptaSUNY Downstate Health Sciences University, Departments of Pathology and Cell Biology, Brooklyn, New York.
Thomas M FishbeinMedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coronavirus InfectionsInflammasomesPandemicsPneumonia, ViralPyroptosisBetacoronavirusCaspase 1COVID-19HumansNLR Family, Pyrin Domain-Containing 3 ProteinRetrospective StudiesSARS-CoV-2Caspase 1InflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinCaspase-1Chronic liver diseaseComorbiditiesCOVID-19InflammasomeLiver cirrhosisLiver transplantationLymphopeniaPyroptosisT cells

Identifiers

PMID32645361
PMCPMC7336919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.