Evidence map›Paper›PMID 32645136›Full record

ArticleBlood advances2020

Clinical efficacy of anakinra to mitigate CAR T-cell therapy-associated toxicity in large B-cell lymphoma.

Paolo Strati, Sairah Ahmed, Partow Kebriaei, Loretta J Nastoupil, Catherine M Claussen, Grace Watson, Sandra B Horowitz, Anne Rain T Brown, Bryan Do, Maria A Rodriguez and 5 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 191 citations in OpenAlex.

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  16. Novel strategies to manage CAR-T cell toxicity.Nature reviews. Drug discovery · 2025
    Review
  17. Review
  18. Deep insight into cytokine storm: from pathogenesis to treatment.Signal transduction and targeted therapy · 2025
    Review
  19. Review
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Paolo StratiDepartment of Lymphoma and Myeloma.
Sairah AhmedDepartment of Lymphoma and Myeloma.
Partow KebriaeiDepartment of Stem Cell Transplantation and Cellular Therapy.
Loretta J NastoupilDepartment of Lymphoma and Myeloma.
Catherine M ClaussenDepartment of Lymphoma and Myeloma.
Grace WatsonDepartment of Lymphoma and Myeloma.
Sandra B HorowitzDivision of Pharmacy, and.
Anne Rain T BrownDivision of Pharmacy, and.
Bryan DoDivision of Pharmacy, and.
Maria A RodriguezDepartment of Lymphoma and Myeloma.
Ranjit NairDepartment of Lymphoma and Myeloma.
Elizabeth J ShpallDepartment of Stem Cell Transplantation and Cellular Therapy.
Michael R GreenDepartment of Lymphoma and Myeloma.
Sattva S NeelapuDepartment of Lymphoma and Myeloma.
Jason R WestinDepartment of Lymphoma and Myeloma.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphoma, B-CellReceptors, Chimeric AntigenHumansImmunotherapy, AdoptiveInterleukin 1 Receptor Antagonist ProteinTreatment OutcomeInterleukin 1 Receptor Antagonist ProteinReceptors, Chimeric Antigen

Identifiers

PMID32645136
PMCPMC7362369
OpenAlexW3041796898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.