Evidence map›Paper›PMID 32645134›Full record

ReviewInvestigative ophthalmology & visual science2020

Focus on Data: Statistical Design of Experiments and Sample Size Selection Using Power Analysis.

Johannes Ledolter, Randy H Kardon

Abstract readReview
In one paragraph

Review in Investigative ophthalmology & visual science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
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  8. See what I mean? Reading visual verbs modulates ocular dynamics.Language, cognition and neuroscience · 2025
    Article
  9. Lifecycle DoE-The Companion for a Holistic Development Process.Bioengineering (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Recognizing Patterns of Nature Contact Associated with Well-Being: An Exploratory Cluster Analysis.International journal of environmental research and public health · 2024
    Article
  13. Article
  14. Simulation-Based Analysis of Trial Design in Regional Anesthesia.Anesthesiology research and practice · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Johannes Ledolter.
Randy H Kardon.

Funding

Center for the Prevention and Treatment of Visual LossI50RX003002 · VA · IOWA CITY VA MEDICAL CENTER · PI RANDY H. KARDON, MARKUS H. KUEHN · 2019 to 2026
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RRD VA I50 RX003002
6 · The paper itself

Abstract

Purpose: To provide information to visual scientists on how to optimally design experiments and how to select an appropriate sample size, which is often referred to as a power analysis. Methods: Statistical guidelines are provided outlining good principles of experimental design, including replication, randomization, blocking or grouping of subjects, multifactorial design, and sequential approach to experimentation. In addition, principles of power analysis for calculating required sample size are outlined for different experimental designs and examples are given for calculating power and factors influencing it. Results: The interaction between power, sample size and standardized effect size are shown. The following results are also provided: sample size increases with power, sample size increases with decreasing detectable difference, sample size increases proportionally to the variance, and two-sided tests, without preference as to whether the mean increases or decreases, require a larger sample size than one-sided tests. Conclusions: This review outlines principles for good experimental design and methods for power analysis for typical sample size calculations that visual scientists encounter when designing experiments of normal and non-Gaussian sample distributions.

Indexed as

Models, StatisticalHumansResearch DesignSample Size

Identifiers

PMID32645134
PMCPMC7425741

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.