Evidence map›Paper›PMID 32644927›Full record

ArticleEuropean journal of rheumatology2020

Validity and reliability of EQ-5D-5L among patients with axial spondyloarthritis in Singapore.

Jun Jie Benjamin Seng, Yu Heng Kwan, Warren Fong, Jie Kie Phang, Nai Lee Lui, Julian Thumboo, Ying Ying Leung

Registry-linked trialAbstract read
In one paragraph

Article in European journal of rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06607497 (Better Risk Perception Via Patient Similarity to Control Hyperglycemia and Sustained by Telemonitoring), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06607497 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Better Risk Perception Via Patient Similarity to Control Hyperglycemia and Sustained by Telemonitoring

TypeinterventionalSponsorSingHealth PolyclinicsRan2024 to 2026Enrolled360ConditionsDiabetes Mellitus, Type 2ArmsIntervention using an AI enabled risk communication tool (PERDICT.AI), Telemonitoring with Primary Tech Enhanced Care (PTEC-DM)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
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  11. Refinement and Validation of a New Patient-Reported Experience Measure for Hearing Loss (My Hearing PREM).Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  12. Article
  13. Article
  14. Measuring disability in multiple sclerosis: the WHODAS 2.0.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  15. Article
  16. Article
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  18. Health-related quality of life among spondyloarthritis and chronic low back pain patients: results from a nationwide population-based survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun Jie Benjamin SengDepartment of Medicine, Duke-NUS Medical School, 8 College Road, Singapore.ORCID http://orcid.org/0000-0002-3039-3816
Yu Heng KwanProgram in Health Services and Systems Research, Duke-NUS Medical School, 8 College Road, Singapore.ORCID http://orcid.org/0000-0001-7802-9696
Warren FongDepartment of Medicine, Duke-NUS Medical School, 8 College Road, Singapore.ORCID http://orcid.org/0000-0003-1891-1892
Jie Kie PhangDepartment of Rheumatology and Immunology, Singapore General Hospital, Outram Road, Singapore.ORCID http://orcid.org/0000-0003-1357-8568
Nai Lee LuiDepartment of Rheumatology and Immunology, Singapore General Hospital, Outram Road, Singapore.ORCID http://orcid.org/0000-0003-4275-1737
Julian ThumbooProgram in Health Services and Systems Research, Duke-NUS Medical School, 8 College Road, Singapore.ORCID http://orcid.org/0000-0001-6712-5535
Ying Ying LeungDepartment of Medicine, Duke-NUS Medical School, 8 College Road, Singapore.ORCID http://orcid.org/0000-0001-8492-6342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to evaluate the reliability and validity of EuroQOL-5 Dimensions-5 Levels (EQ-5D-5L) among patients with axial spondyloarthritis (SpA) in Singapore.

methodsA cross-sectional study was conducted involving patients with axial SpA in an Asian tertiary hospital from 2017 to 2018. This study followed the COnsensus-based Standards for selection of health Measurement Instruments framework. Construct validity was evaluated by testing 22 a priori hypotheses with other patient-reported outcomes measures. Cronbach's alpha was used to estimate the internal consistency of the EQ-5D-5L, while its test-retest reliability was assessed using weighted kappa and the intraclass correlation coefficient (ICC). The measurement error was assessed by analyzing minimal detectable change (MDC).

resultsThe median age of included patients (n=118) was 35 years (interquartile range: 28, 49). Ninety-six (81.4%) patients were male, while 112 (94.9%) patients were of Chinese ethnicity. The EQ-5D-5L demonstrated good internal consistency with a Cronbach's alpha of 0.79. The test-retest reliability of the EQ-5D-5L was good with a weighted kappa of ≥0.61 for mobility, self-care, usual activities, and anxiety/depression; the ICC was 0.92 and 0.99 for the EQ-5D-5L index and visual analog scale (VAS) scores, respectively. The weighted kappa for the EQ-5D-5L pain/discomfort was moderate [0.53, 95% confidence interval: 0.41-0.60]. The MDC for EQ-5D-5L index and VAS scores was 0.06 and 4.5, respectively. Convergent validity was supported as all hypotheses were confirmed in the results.

conclusionThis study supports EQ-5D-5L as a valid and reliable instrument for assessing health-related quality of life among patients with axial SpA in Singapore.

Identifiers

PMID32644927
PMCPMC7343224

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.