Evidence map›Paper›PMID 32644275›Full record

ReviewReviews in medical virology2020

Current pharmacological modalities for management of novel coronavirus disease 2019 (COVID-19) and the rationale for their utilization: A review.

Richard A Giovane, Shadi Rezai, Ellen Cleland, Cassandra E Henderson

Open access · greenAbstract readReview
In one paragraph

Review in Reviews in medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Polypharmacy among COVID-19 patients: A systematic review.Journal of the American Pharmacists Association : JAPhA
    Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Richard A GiovaneDepartment of Family Medicine, Regional Medical Center of Central Alabama, Greenville, Alabama, USA.ORCID https://orcid.org/0000-0002-8547-2693
Shadi RezaiDepartment of OB/GYN, Valley Community Healthcare, North Hollywood, California, USA.ORCID https://orcid.org/0000-0001-8498-565X
Ellen ClelandDepartment of Family Medicine, University of Alabama, Tuscaloosa, Alabama, USA.
Cassandra E HendersonGarden OB/GYN, Mercy Medical Center, New York, New York, USA.
IPC Healthcare · USMercy Medical Center · USRegional Medical Center · USUniversity of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 has caused a pandemic which is putting strain on the health-care system and global economy. There is much pressure to develop both preventative and curative therapies for SARS-CoV-2 as there is no evidence to support therapies to improve outcomes in patients with SARS-CoV-2. Medications that inhibit certain steps of virus life cycle that are currently used to treat other illnesses such as Malaria, Ebola, HIV and Hepatitis C are being studied for use against SARS-CoV-2. To date, data is limited for medications that facilitate clinical improvement of COVID-19 infections.

Indexed as

PandemicsAdenosine MonophosphateAlanineAngiotensin-Converting Enzyme 2Antibodies, Monoclonal, HumanizedAntiviral AgentsBetacoronavirusCoronavirus InfectionsCOVID-19Disease ProgressionDrug CombinationsDrug RepositioningEstersGabexateGene Expression RegulationGuanidinesACE2 protein, humanAdenosine MonophosphateAlanineAngiotensin-Converting Enzyme 2Antibodies, Monoclonal, HumanizedAntiviral AgentscamostatDrug CombinationsEstersGabexateGuanidinesHydroxychloroquineIndolesLopinavirlopinavir-ritonavir drug combinationPeptidyl-Dipeptidase AremdesivirRitonavirSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Sulfidestocilizumabumifenovir2019-nCoVacetazolamideacute respiratory distress syndrome (ARDS)autoimmunecamostat mesylatechloroquineCOVID-19high altitude pulmonary edema (HAPE)hydroxychloroquineLopinavir/Ritonavirnovel coronavirus 2019pandemicRemdesivirRNA-dependent RNA polymerase inhibitorsSARS coronavirus (SARS-CoV)SARS CoV-2severe acute respiratory syndrome (SARS)Umifenovir

Identifiers

PMID32644275
PMCPMC7361252
OpenAlexW3042183491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.