Evidence map›Paper›PMID 32644043›Full record

ArticleeLife2020

Infant and adult SCA13 mutations differentially affect Purkinje cell excitability, maturation, and viability in vivo.

Jui-Yi Hsieh, Brittany N Ulrich, Fadi A Issa, Meng-Chin A Lin, Brandon Brown, Diane M Papazian

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Kv3.3 Expression Enhanced by a Novel Variant in the Kozak Sequence ofInternational journal of molecular sciences · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Ankyrin-R Links Kv3.3 to the Spectrin Cytoskeleton and Is Required for Purkinje Neuron Survival.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  11. Article
  12. NovelInternational journal of molecular sciences · 2021
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jui-Yi Hsieh *Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, United States.
Brittany N Ulrich *Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, United States.
Fadi A IssaDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, United States.ORCID 0000-0001-5234-5850
Meng-Chin A LinDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, United States.
Brandon BrownDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, United States.
Diane M PapazianDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, United States.ORCID 0000-0001-8194-5740
University of California, Los Angeles · US

Funding

Kv3.3 K+ Channels and Neuronal Excitability in Spinocerebellar Ataxia Type 13R01NS058500 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PAPAZIAN, DIANE M · 2008 to 2011
$1.3M
NIH HHS R01 NS058500NINDS NIH HHS R01 NS058500
6 · The paper itself

Abstract

Mutations in

Indexed as

MutationAge FactorsAnimalsCell SurvivalCerebellumDisease Models, AnimalPurkinje CellsShaw Potassium ChannelsSpinocerebellar AtaxiasZebrafishZebrafish Proteinskcnc3a protein, zebrafishShaw Potassium ChannelsZebrafish Proteinscerebellar developmentcerebellumdegenerationexcitabilityneurosciencePurkinje cellspinocerebellar ataxiazebrafish

Identifiers

PMID32644043
PMCPMC7386905
OpenAlexW3040715897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.