Evidence map›Paper›PMID 32643416›Full record

ArticleHypertension (Dallas, Tex. : 1979)2020

SARS-CoV-2 Receptor ACE2 (Angiotensin-Converting Enzyme 2) Is Upregulated in Colonic Organoids From Hypertensive Rats.

Jing Li, Bruce R Stevens, Elaine M Richards, Mohan K Raizada

Open access · greenAbstract readLetterComment
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Hypertension (Dallas, Tex. : 1979) · 2021
    Article
  7. Gut-brain-bone marrow axis in hypertension.Current opinion in nephrology and hypertension · 2021
    Review
  8. Article
  9. BFunction (Oxford, England) · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jing LiFrom the Department of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville.
Bruce R StevensFrom the Department of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville.
Elaine M RichardsFrom the Department of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville.
Mohan K RaizadaFrom the Department of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville.
University of Florida · US

Funding

Brain-Gut Microbiome-Immune Axis in HypertensionR01HL132448 · NHLBI · UNIVERSITY OF FLORIDA · PI Carl J Pepine, Steven Michael Smith · 2016 to 2026
$4.5M
BRAIN ANGIOTENSIN IN HYPERTENSIVE NEURONS IN CULTURER01HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K., SUMNERS, COLIN · 1985 to 2017
$4.3M
Angiotensin-Converting Enzyme2 in Vascular Endothelial FunctionR01HL102033 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2010 to 2019
$4.3M
Vascular Reparative Mechanism by ACE2/Ang-(1-7)in DiabetesR01HL110170 · NHLBI · UNIVERSITY OF FLORIDA · PI GRANT, MARIA BARTOLOMEO · 2011 to 2015
$2.2M
NHLBI NIH HHS R01 HL033610NHLBI NIH HHS R01 HL102033NHLBI NIH HHS R01 HL110170NHLBI NIH HHS R01 HL132448
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coronavirus InfectionsOrganoidsPandemicsPeptidyl-Dipeptidase APneumonia, ViralAngiotensinsAnimalsBetacoronavirusChinaCOVID-19HumansInpatientsRatsRetrospective StudiesRisk FactorsSARS-CoV-2AngiotensinsPeptidyl-Dipeptidase Aangiotensinscomorbiditycoronavirus diseaseorganoidspopulation

Identifiers

PMID32643416
PMCPMC7375174
OpenAlexW3040965077

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.