Evidence map›Paper›PMID 32643133›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Neurological diseases as mortality predictive factors for patients with COVID-19: a retrospective cohort study.

Jong-Moon Hwang, Ju-Hyun Kim, Jin-Sung Park, Min Cheol Chang, Donghwi Park

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 18 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 18 syntheses or guidelines pooled it, 96 citations in OpenAlex.

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  16. The Association of Cerebrovascular Disease with Adverse Outcomes in COVID-19 Patients: A Meta-Analysis Based on Adjusted Effect Estimates.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020
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  20. Decline in dementia patients during the COVID-19 pandemic: A cohort study in Taiwan.Journal of the Chinese Medical Association : JCMA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jong-Moon Hwang *Department of Rehabilitation Medicine, Kyungpook National University Hospital, Daegu, South Korea.
Ju-Hyun Kim *Department of Rehabilitation Medicine, Kyungpook National University Hospital, Daegu, South Korea.
Jin-Sung ParkDepartment of Neurology, School of medicine, Kyungpook National University Chilgok hospital, Kyungpook National University, Daegu, Republic of Korea.
Min Cheol ChangDepartment of Rehabilitation Medicine, College of Medicine, Yeungnam University, Daegu, Republic of Korea. wheel633@ynu.ac.kr.
Donghwi ParkDepartment of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, 877 Bangeojinsunghwndo-ro, Dong-gu, Ulsan, 44033, Republic of Korea. bdome@hanmail.net.ORCID http://orcid.org/0000-0002-7724-4682
Kyungpook National University Hospital · KRUlsan College · KRYeungnam University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the current study, we evaluated factors that increase the coronavirus disease (COVID-19) patient death rate by analyzing the data from two cohort hospitals. In addition, we studied whether underlying neurological diseases are risk factors for death.

methodsIn this retrospective cohort study, we included 103 adult inpatients (aged ≥ 18 years). We evaluated differences in demographic data between surviving and non-surviving COVID-19 patients.

resultsIn a multivariate logistic analysis, age and the presence of chronic lung disease and Alzheimer's dementia (AD) were the only significant parameters for predicting COVID-19 non-survival (p < 0.05). However, hypertension, coronary vascular disease, dyslipidemia, chronic kidney disease, diabetes, and history of taking angiotensin II receptor blockers (ARBs) or angiotensin-converting enzyme (ACE) inhibitors, as well as nonsteroidal anti-inflammatory drugs (NSAIDs), were not significantly associated with the death of COVID-19 patients. The optimal cutoff value obtained from the maximum Youden index was 70 (sensitivity, 80.77%; specificity, 61.04%), and the odds ratio of non-survival increased 1.055 fold for every year of age.

conclusionsClinicians should closely monitor and manage the symptoms of COVID-19 patients who are over the age of 70 years or have chronic lung disease or AD.

Indexed as

BetacoronavirusAgedAged, 80 and overAge FactorsCohort StudiesCoronavirus InfectionsCOVID-19FemaleHumansLung DiseasesMaleMiddle AgedMortalityNervous System DiseasesPandemicsPneumonia, ViralAlzheimer’s dementiaChronic lung diseaseCoronavirusCOVID-19

Identifiers

PMID32643133
PMCPMC7342552
OpenAlexW3040825973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.