SynthesisOral and maxillofacial surgery2020
Efficacy of preoperative antibiotics in prevention of dental implant failure: a Meta-analysis of randomized controlled trials.
Synthesis in Oral and maxillofacial surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Is routine antibiotic prophylaxis warranted in dental implant surgery to prevent early implant failure? - a systematic review.BMC oral health · 2024Pooled it
- Short implants compared to regular dental implants after bone augmentation in the atrophic posterior mandible: umbrella review and meta-analysis of success outcomes.International journal of implant dentistry · 2023Pooled it
- Antibiotic Use in Dental Implant Procedures: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Effects of clindamycin and amoxycillin as prophylaxis against early implant failure: double-blinded randomized clinical trial.Clinical oral investigations · 2024Trial
- Effect of antibiotic prophylaxis in dental implant surgery: A multicenter placebo-controlled double-blinded randomized clinical trial.Clinical implant dentistry and related research · 2022Trial
- Antibiotic prophylaxis in dental implant surgery - A qualitative study on the attitudes and routines of Swedish dentists.BMC oral health · 2025Article
- A Multicenter Study of Factors Related to Early Implant Failures-Part 1: Implant Materials and Surgical Techniques.Clinical implant dentistry and related research · 2025Article
- Environmental, Microbiological, and Immunological Features of Bacterial Biofilms Associated with Implanted Medical Devices.Clinical microbiology reviews · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDental implants are commonly used for replacement of missing teeth. Despite the published data highlighting the high success rate of dental implants, failures do occur. Some of these failures are believed to be a result of bacterial contamination at the site of implant insertion. Various antibiotic regimens have already been suggested to prevent failure due to infection.
objectiveThis meta-analysis aims to examine the efficacy of preoperative antibiotics in prevention of dental implant failure secondary to infections. METHODOLOGY: An exhaustive search was conducted on electronic database including PubMed Medline, Google Scholar, Scopus, and Cochrane on July 15, 2019. All the randomized controlled trials (RCT) comparing preoperative antibiotics with no antibiotics/placebo in dental implants were included in the study. The primary outcome for assessment was implant failure. A random effect meta-analysis was conducted for risk ratios of dichotomous data.
resultsA total 8544 abstracts were screened following which 16 full text articles were reviewed and 5 RCTs were included in the analysis. Meta-analysis results indicated that the preoperative antibiotics resulted in statistically significantly lower number of implant failures.
conclusionPreoperative antibiotics effectively reduce the implant failure rate. However, it is recommended to conduct large-scale RCT to determine the efficacy of preoperative antibiotics in dental implants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.