Evidence map›Paper›PMID 32643018›Full record

ArticleBreast cancer (Tokyo, Japan)2021

Investigation of the significance of population-based breast cancer screening among women aged under 40 years.

Mai Okazaki, Hiroko Bando, Eriko Tohno, Yuka Kujiraoka, Akiko Iguchi-Manaka, Emika Ichioka, Yukiko Tsushima, Hiroshi Watanabe, Hisato Hara

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Breast cancer (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mai OkazakiGraduate School of Comprehensive Human Sciences Majors of Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.ORCID http://orcid.org/0000-0002-7396-0454
Hiroko BandoDepartment of Breast and Endocrine Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan. bando@md.tsukuba.ac.jp.
Eriko TohnoTsukuba International Breast Clinic, Tsukuba, Ibaraki, Japan.
Yuka KujiraokaDepartment of Radiology, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan.
Akiko Iguchi-ManakaDepartment of Breast and Endocrine Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Emika IchiokaDepartment of Breast and Endocrine Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Yukiko TsushimaDepartment of Breast and Endocrine Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Hiroshi WatanabeIbaraki Health Service Association Institute, Mito, Ibaraki, Japan.
Hisato HaraDepartment of Breast and Endocrine Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOwing to low incidence rates, population-based breast cancer screening is not recommended by many municipalities in Japan for women aged < 40 years. To evaluate the usefulness of screening in women aged < 40 years, we investigated the results of population-based breast cancer screening among young women performed in the Ibaraki Prefecture.

methodsData regarding histological characteristics, recall rates, cancer detection rates, positive predictive values, tumor categories, and status of lymph node metastases were obtained from population-based screening data from Ibaraki Health Service Association Institute. The "number needing to be screened" (NNS) was determined; using Pearson's chi-squared test, these data were compared between women aged < 40 years and > 40 years.

resultsThe data of 428,560 women were evaluated. Cancer detection rates were significantly lower and the NNS and proportion of women with tumor category T2 or higher was significantly increased in women aged < 40 years than in those aged > 40 years (0.06% vs. 0.21%, 1505 vs. 281-439, and 28.9% vs. 6.3%, respectively; all, p < 0.05). The proportion of early-stage cancers was lower in women aged < 40 years than in those > 40 years, but this was not significant.

conclusionsThese results suggest that population-based breast cancer screening should not be recommended for women aged < 40 years. To reduce the breast cancer-related mortality rate in young women and ensure efficient use of limited medical resources in Japan, a more efficient surveillance system, based on genetic propensity and family history, needs to be established.

Indexed as

Practice Guidelines as TopicAdultAge FactorsBreastBreast NeoplasmsEarly Detection of CancerFemaleHumansIncidenceJapanLymphatic MetastasisLymph NodesMammographyMass ScreeningMiddle AgedNeoplasm StagingBreast cancerJapanScreeningYoung women

Identifiers

PMID32643018

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