Evidence map›Paper›PMID 32642839›Full record

SynthesisJournal of anesthesia2020

The analgesic efficacy of quadratus lumborum block in caesarean delivery: a meta-analysis and trial sequential analysis.

Narinder P Singh, Jeetinder K Makkar, Anuradha Borle, David Monks, Basavana Gouda Goudra, Andres Zorrilla-Vaca, Preet Mohinder Singh

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of anesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Narinder P SinghDepartment of Anaesthesia, MM(DU), Mullana, Ambala, India.
Jeetinder K MakkarDepartment of Anaesthesia and Intensive Care, PGIMER, Sector 12, Chandigarh, 160012, India. jeet1516@gmail.com.ORCID http://orcid.org/0000-0001-8159-5920
Anuradha BorleDepartment of Anesthesia, Washington University in Saint Louis, Saint Louis, MO, USA.
David MonksDepartment of Anesthesia, Washington University in Saint Louis, Saint Louis, MO, USA.
Basavana Gouda GoudraDepartment of Anesthesia, Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Andres Zorrilla-VacaDepartment of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, MD, USA.
Preet Mohinder SinghDepartment of Anesthesia, Washington University in Saint Louis, Saint Louis, MO, USA.
Washington University in St. Louis · USHospital of the University of Pennsylvania · USJohns Hopkins Hospital · USPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeQuadratus lumborum block (QLB) has recently gained popularity for postoperative analgesia after cesarean delivery (CD) as it provides both visceral and somato-sensory blockade of the abdomen. Aim of this meta-analysis was to evaluate the analgesic potential of QLB after CD.

methodsElectronic database from inception to December 2019 was searched systematically for randomized-controlled trials comparing QLB with injection of inactive solution in women undergoing CD. Primary outcome was consumption of morphine at 24 h. Morphine consumption at 48 h, dynamic and static pain scores at various time intervals were the secondary outcomes studied.

resultsSeven trials met the inclusion criteria. Morphine consumption was reduced significantly with QLB in comparison to sham or no block at 24 h (mean difference [MD] - 9.84 mg; 95% confidence interval [CI] - 18.16, - 0.50; p = 0.04; I

conclusionQLB significantly reduces opioid requirements in CD and may have analgesic effects lasting 24 h.

Indexed as

Nerve BlockPostoperative PainAnesthetics, LocalCesarean SectionFemaleHumansMorphinePregnancyAnesthetics, LocalMorphineAnalgesiaCesarean deliveryMorphinePostoperative painQuadratus lumborum block

Identifiers

PMID32642839
OpenAlexW3041369206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.