ReviewAmerican journal of cancer research2020
METTL3 plays multiple functions in biological processes.
Open access · greenAbstract readReview
In one paragraph
Review in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
137 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.
- Disrupting Mechanisms that Regulate Genomic Repeat Elements to Combat Cancer and Drug Resistance.Frontiers in cell and developmental biology · 2022Pooled it
- Virtual screening and experimental validation of a METTL3-targeting peptide withJournal of enzyme inhibition and medicinal chemistry · 2026Article
- METTL3 Confers Ischemia/Reperfusion-Caused Myocardial Injury by Triggering Ferroptosis via Regulating the lncRNA SNHG14/miR-195a-5p/ACSL4 Axis.Cardiovascular drugs and therapy · 2026Article
- The periphery of nuclear speckles defines a spatially and temporally regulated compartment of long-lived intron-retained RNAs that resolves during mitosis.Nature cell biology · 2026Article
- The miR-338-5p/METTL3 axis regulates m6A modification to inhibit tumor progression in triple-negative breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- RNA methyltransferase 3 drives pancreatic acinar cell carcinoma growth and is a therapeutic target.Signal transduction and targeted therapy · 2026Article
- WTAP -mediated N6‑methylation of TRAF6 Facilitates Polycystic Ovary Syndrome by Inducing Ferroptosis.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Decoding Protein-Methylating METTLs in Humans: Structural, Functional, and Disease Insights over the Past Decade.International journal of molecular sciences · 2026Review
- Integrated multi-omics analysis reveals tumor-suppressive phenotypes and associated transcriptomic remodeling upon METTL3 overexpression in A549 lung cancer cells.Translational cancer research · 2026Article
- Neuromodulatory role and therapeutic potential of N 6 -methyladenosine RNA methylation in neurodegenerative diseases.Neural regeneration research · 2026Article
- The crucial role of m6A methylation modification in nasopharyngeal carcinoma.Discover oncology · 2026Review
- E2F2 suppresses cell senescence and promotes odontogenic differentiation in dental pulp stem cells by stabilizing METTL3.Odontology · 2026Article
- The asymmetrical ROS-METTL3-ESR1 axis in paraspinal muscle progenitor cells determines the progression of adolescent idiopathic scoliosis.Experimental & molecular medicine · 2026Article
- METTL14 Promotes Lipid Synthesis in Dairy Goat Mammary Epithelial Cells by TargetingAnimals : an open access journal from MDPI · 2026Article
- Deficiency of METTL3 alleviates excessive autophagy and apoptosis in mice with slow transit constipation and glutamic acid-induced interstitial cells of Cajal via the activation of PI3K/AKT pathway.Journal of molecular histology · 2026Article
- Epigenetics of Malignant Melanoma: Mechanisms, Diagnostic Approaches and Therapeutic Applications.Oncology research · 2026Review
- METTL3 mediates m6A methylation of LCN2 through IGF2BP3 to promote ferroptosis in chronic obstructive pulmonary disease.Hereditas · 2025Article
- USP25 deubiquitinates cytosolic METTL3 to impede glioma proliferation via an m6A-independent pathway.iScience · 2025Article
- Bladder Cancer Growth is Inhibited by Upregulating CircFUT8 through the METTL14/FMR1 Signaling Pathway.Cell biochemistry and biophysics · 2025Article
- METTL3-Mediated m6A Methylation of USP21 Contributes to Hepatocellular Carcinoma Progression by Stabilizing H2BFS Through Deubiquitination.Biochemical genetics · 2025Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Shuiping LiuHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Lvjia ZhuoHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Jianjun WangHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Qin ZhangHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Qiujie LiHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Guohua LiHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Lili YanHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Ting JinHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Ting PanHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Xinbing SuiHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Qun LvHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Tian XieHolistic Integrative Pharmacy Institutes of Medicine School, Department of Respiratory Medicine of Affiliated Hospital, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Hangzhou Normal University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
N
Indexed as
biological processcancer therapydiagnostic biomarkerm6A modificationMETTL3
Identifiers
PMID
32642280PMC
PMC7339281OpenAlex
W3042216655What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.