Evidence map›Paper›PMID 32642173›Full record

ArticleJournal of thoracic disease2020

Left ventricular assist device-associated infections: incidence and risk factors.

Andréa Rahal, Yvon Ruch, Nicolas Meyer, Stéphanie Perrier, Tam Hoang Minh, Clément Schneider, Thierry Lavigne, Sandrine Marguerite, Gharib Ajob, Mircea Cristinar and 3 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Clinical outcomes of modified left ventricular assist device driveline management.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Article
  6. Recent Developments in Ventricular Assist Device Therapy.Reviews in cardiovascular medicine · 2025
    Review
  7. Infections in Patients with Mechanical Circulatory Support.Infectious disease clinics of North America · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Physical Approaches to Prevent and Treat Bacterial Biofilm.Antibiotics (Basel, Switzerland) · 2022
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andréa RahalEquipe Opérationnelle D'Hygiène, CHU de Strasbourg, 1, Place de l'Hôpital, 67091, Strasbourg, France.
Yvon RuchDepartment of Infectious Diseases, University Hospital, Nouvel Hôpital Civil, Strasbourg, France.
Nicolas MeyerICube, UMR7357, Université de Strasbourg, Strasbourg, France.
Stéphanie PerrierDepartment of Cardiovascular Surgery, University Hospitals of Strasbourg, Strasbourg, France.
Tam Hoang MinhDepartment of Cardiovascular Surgery, University Hospitals of Strasbourg, Strasbourg, France.
Clément SchneiderDepartment of Cardiovascular Surgery, University Hospitals of Strasbourg, Strasbourg, France.
Thierry LavigneEquipe Opérationnelle D'Hygiène, CHU de Strasbourg, 1, Place de l'Hôpital, 67091, Strasbourg, France.
Sandrine MargueriteDepartment of Anesthesia and Intensive Care Unit, University Hospitals of Strasbourg, Strasbourg, France.
Gharib AjobDepartment of Anesthesia and Intensive Care Unit, University Hospitals of Strasbourg, Strasbourg, France.
Mircea CristinarDepartment of Anesthesia and Intensive Care Unit, University Hospitals of Strasbourg, Strasbourg, France.
Eric EpaillyDepartment of Cardiovascular Surgery, University Hospitals of Strasbourg, Strasbourg, France.
Jean-Philippe MazzucotelliDepartment of Cardiovascular Surgery, University Hospitals of Strasbourg, Strasbourg, France.
Michel KindoDepartment of Cardiovascular Surgery, University Hospitals of Strasbourg, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular assist device (LVAD)-associated infections are major complications that can lead to critical outcomes. The aims of this study were to assess the incidence of and to determine the risk factors for LVAD-associated infections.

methodsWe included all consecutive patients undergoing LVAD implantation between January 1, 2010, and January 1, 2019, in a single institution. Infection-related data were retrospectively collected by review of patient's medical files. LVAD-associated infections were classified into three categories: percutaneous driveline infections, pocket infections and pump and/or cannula infections.

resultsWe enrolled 72 patients. Twenty-one (29.2%) patients presented a total of 32 LVAD-associated infections. Eight (38.1%) patients had more than one infection. Five (62.5%) pocket infections and one (50.0%) pump and/or cannula infection were preceded by a driveline infection. The median delay between the operation and LVAD-associated infection was 6.5 (1.4-12.4) months. The probability of having a LVAD-associated infection at one year after receiving an implant was 26.6% (95% CI: 17.5-40.5%). Percutaneous driveline infections represented 68.7% of all LVAD-associated infections.

conclusionsLVAD-associated infections remain an important complication and are mostly represented by percutaneous driveline infections. Gram-positive cocci are the main pathogens isolated in microbiological samples. Patients with LVAD-associated infections are more frequently colonized with multidrug-resistant bacteria.

Indexed as

artificial heart ventriclecareHeart failureinfectionpostoperativepostoperative wound

Identifiers

PMID32642173
PMCPMC7330372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.