ArticleJournal of thoracic disease2020
Vasoplegia following heart transplantation and left ventricular assist device explant is not associated with inferior outcomes.
Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Definitions for Vasoplegia Associated With On-Pump Cardiac Surgery: A Systematic Review With Meta-Analysis.Critical care explorations · 2025Pooled it
- Outcomes and Risk Factors for Postoperative Vasoplegia Following Implant of Left Ventricular Assist Devices.Journal of the American Heart Association · 2026Article
- Heart transplantation outcomes with donation after circulatory death in patients with left ventricular assist device.ESC heart failure · 2025Article
- Application of donor predicted heart mass in heart transplant recipients with left ventricular assist device.JHLT open · 2024Article
- Vasoplegia from Continuous Flow Left Ventricular Assist Devices.Current cardiology reports · 2021Review
- Ketamine, interleukin-6, and vasoplegia: Is prevention the best medicine?Annals of cardiac anaesthesiaArticle
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVasoplegia has been associated with inferior outcomes following heart transplantation (HTx). This observational study was designed to investigate outcomes in recipients with vasoplegia following left ventricular assist device (LVAD) explant HTx.
methodsPatients undergoing LVAD explant followed by HTx from 01/2013-12/2018 at our centre were included. Vasoplegia was defined as the requirement for high dose vasopressor [noradrenaline (>0.5 μg/kg/min) and vasopressin (>1 U/h)] over the first 24 hours following HTx. Demographic and outcome data were retrieved from the transplant unit database.
resultsDuring the study period 24 patients underwent LVAD explant HTx. Of these, 13 (54.2%) developed vasoplegia. Both groups had similar duration of LVAD support (median 684
conclusionsVasoplegia is seen with a high incidence in HTx recipients bridged with an LVAD. This appears to be associated with the presence of driveline infections. Early aggressive management is advocated, resulting in equivalent 1-year survival to those patients not developing vasoplegia.
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