Evidence map›Paper›PMID 32642138›Full record

ArticleJournal of thoracic disease2020

Low platelet count is a risk factor of postoperative pneumonia in patients with type A acute aortic dissection.

Run Yao, Xianglin Liu, Yi He, Cheng Mei, Yamei Shen, Qinru Zhan, Lingjin Huang, Bijuan Li, Ning Li

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Run YaoDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Xianglin LiuDepartment of Anesthesiology, Changsha Maternal and Child Health Hospital, Changsha 410007.
Yi HeDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Cheng MeiDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Yamei ShenDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Qinru ZhanDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Lingjin HuangDepartment of Cardiac Surgery, Xiangya Hospital, Central South University, Changsha 410007, China.
Bijuan LiDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Ning LiDepartment of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410007, China.
Central South University · CNXiangya Hospital Central South University · CNChangsha Hospital for Maternal and Child Health Care · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have already established that low platelet count is related to adverse outcomes in patients with type A acute aortic dissection (AAAD). However, there are yet limited studies investigating the association of platelet count and the risk of postoperative pneumonia in AAAD patients.

methodsThis retrospective cohort study was conducted in Xiangya Hospital of Central South University from January 2014 to May 2019. Clinical and laboratory data were collected. The correlation between platelet count and postoperative pneumonia was analyzed using multivariate logistic regression and the area under the receiver operating characteristic curve (AUC) was used to assess the predictive power of platelet count on pneumonia.

resultsA total of 268 patients with AAAD were enrolled. The overall incidence of pneumonia was 36.94% (n=99). Multivariate logistic regression revealed that platelet count was negatively associated with the risk of postoperative pneumonia (OR 0.93; 95% CI: 0.88-0.98) after adjusting for the confounders. Compared to the lowest platelet count tertile (T1), medium platelet count (T2) and highest platelet count (T3) had a lower risk of postoperative pneumonia after adjusting for the confounders (OR 0.80, 95% CI: 0.40-1.60; OR 0.30, 95% CI: 0.13-0.66; respectively). A similar trend was observed when the platelet count was handled as categorical variables (tertiles). The area under the ROC curve was 0.635 (95% CI: 0.565-0.707), with a sensitivity of 76.77%, a specificity of 50.89% and an accuracy of 60.45%.

conclusionsOur findings indicate that low platelet count is an independent risk factor of postoperative pneumonia in patients with AAAD and has a specific predictive power on the risk of postoperative pneumonia.

Indexed as

Platelet countpostoperative pneumoniapredictortype A acute aortic dissection (AAAD)

Identifiers

PMID32642138
PMCPMC7330411
OpenAlexW3020223755

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.