ArticleJournal of thoracic disease2020
Low platelet count is a risk factor of postoperative pneumonia in patients with type A acute aortic dissection.
Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Development and validation of a risk prediction model for postoperative pneumonia in adult patients undergoing Stanford type A acute aortic dissection surgery: a case control study.Journal of cardiothoracic surgery · 2022Trial
- Clinical and Perioperative Determinants of Postoperative Pneumonia After Craniotomy for Tumor Resection.Journal of clinical medicine · 2026Article
- Clinical presentation, aetiological characteristics, risk factors and in-hospital outcome of nosocomial infection following acute aortic dissection surgery in adult patients.BMC cardiovascular disorders · 2025Article
- Platelet-to-white blood cell ratio as a predictor of postoperative outcomes in acute type A aortic dissection: a single-center retrospective analysis.Frontiers in cardiovascular medicine · 2025Article
- Article
- Predictors and outcomes of postoperative tracheostomy in patients undergoing acute type A aortic dissection surgery.BMC cardiovascular disorders · 2022Article
- Occurrence and role of lung megakaryocytes in infection and inflammation.Frontiers in immunology · 2022Review
- Pneumonia After Cardiovascular Surgery: Incidence, Risk Factors and Interventions.Frontiers in cardiovascular medicine · 2022Review
- High platelet distribution width is an independent risk factor of postoperative pneumonia in patients with type A acute aortic dissection.Frontiers in cardiovascular medicine · 2022Article
- U-shaped relationship between platelet-lymphocyte ratio and postoperative in-hospital mortality in patients with type A acute aortic dissection.BMC cardiovascular disorders · 2021Article
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Authors and funding
9 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have already established that low platelet count is related to adverse outcomes in patients with type A acute aortic dissection (AAAD). However, there are yet limited studies investigating the association of platelet count and the risk of postoperative pneumonia in AAAD patients.
methodsThis retrospective cohort study was conducted in Xiangya Hospital of Central South University from January 2014 to May 2019. Clinical and laboratory data were collected. The correlation between platelet count and postoperative pneumonia was analyzed using multivariate logistic regression and the area under the receiver operating characteristic curve (AUC) was used to assess the predictive power of platelet count on pneumonia.
resultsA total of 268 patients with AAAD were enrolled. The overall incidence of pneumonia was 36.94% (n=99). Multivariate logistic regression revealed that platelet count was negatively associated with the risk of postoperative pneumonia (OR 0.93; 95% CI: 0.88-0.98) after adjusting for the confounders. Compared to the lowest platelet count tertile (T1), medium platelet count (T2) and highest platelet count (T3) had a lower risk of postoperative pneumonia after adjusting for the confounders (OR 0.80, 95% CI: 0.40-1.60; OR 0.30, 95% CI: 0.13-0.66; respectively). A similar trend was observed when the platelet count was handled as categorical variables (tertiles). The area under the ROC curve was 0.635 (95% CI: 0.565-0.707), with a sensitivity of 76.77%, a specificity of 50.89% and an accuracy of 60.45%.
conclusionsOur findings indicate that low platelet count is an independent risk factor of postoperative pneumonia in patients with AAAD and has a specific predictive power on the risk of postoperative pneumonia.
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