Evidence map›Paper›PMID 32642004›Full record

ArticleTheranostics2020

Focused Ultrasound Hyperthermia Augments Release of Glioma-derived Extracellular Vesicles with Differential Immunomodulatory Capacity.

Natasha D Sheybani, Alec J Batts, Alexander S Mathew, E Andrew Thim, Richard J Price

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Review
  3. Focused ultrasound for brain metastases.Neuro-oncology advances · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Characterization of microbubble cavitation in theranostic ultrasound-mediated blood-brain barrier opening for gene delivery.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Extracellular Vesicles for Disease Treatment.International journal of nanomedicine · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Engineering Versatile Nanomedicines for Ultrasonic Tumor Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Natasha D SheybaniDepartment of Biomedical Engineering; University of Virginia, Charlottesville, VA 22908.
Alec J BattsDepartment of Biomedical Engineering; University of Virginia, Charlottesville, VA 22908.
Alexander S MathewDepartment of Biomedical Engineering; University of Virginia, Charlottesville, VA 22908.
E Andrew ThimDepartment of Biomedical Engineering; University of Virginia, Charlottesville, VA 22908.
Richard J PriceDepartment of Biomedical Engineering; University of Virginia, Charlottesville, VA 22908.
University of Virginia Medical Center · US

Funding

Immunotherapeutic Nanoparticle Delivery to Melanoma With MR-Guided Focused UltrasoundR01CA197111 · NCI · UNIVERSITY OF VIRGINIA · PI BULLOCK, TIMOTHY N, ENGELHARD, VICTOR H · 2015 to 2019
$2.6M
MRI-Guided miRNA Nanoparticle Delivery to Glioblastoma With Focused UltrasoundR01EB020147 · NIBIB · UNIVERSITY OF VIRGINIA · PI HANES, JUSTIN S., PRICE, RICHARD J. · 2015 to 2018
$2.4M
Molecular Electron Microscopy Core Facility ImprovementsG20RR031199 · NCRR · UNIVERSITY OF VIRGINIA · PI SHUPNIK, MARGARET A · 2010 to 2010
$2.0M
Leveraging MR-Guided Focused Ultrasound to Potentiate Immunotherapy for GBMR21CA226607 · NCI · UNIVERSITY OF VIRGINIA · PI BULLOCK, TIMOTHY N · 2019 to 2020
$383k
Focused Ultrasound and Multifunctional Nanoparticle Vaccines as Adjuvant Strategies for Cancer ImmunotherapyF99CA234954 · NCI · UNIVERSITY OF VIRGINIA · PI SHEYBANI, NATASHA DIBA · 2018 to 2019
$81k
NCI NIH HHS F99 CA234954NCI NIH HHS R01 CA197111NCI NIH HHS R21 CA226607NCRR NIH HHS G20 RR031199NIBIB NIH HHS R01 EB020147
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorCryoelectron MicroscopyDendritic CellsExtracellular VesiclesGliomaHigh-Intensity Focused Ultrasound AblationHumansHyperthermia, InducedImmunity, InnateInterleukin-12MiceProteomicsT-Lymphocytes, Helper-InducerTumor EscapeUp-RegulationInterleukin-12cytokineexosomeextracellular vesiclesFocused ultrasoundglioma

Identifiers

PMID32642004
PMCPMC7330848
OpenAlexW3040036203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.