Evidence map›Paper›PMID 32641985›Full record

ArticleTheranostics2020

Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeability.

Shen Dai, Fengming Liu, Zhongnan Qin, Jinyan Zhang, Jiayi Chen, Wen-Xing Ding, Dechun Feng, Yong Ji, Xuebin Qin

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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  5. Review
  6. Enhancing CD8Biomolecules · 2025
    Article
  7. Transcriptomic profiling of Kupffer cells exposed toFood and waterborne parasitology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
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  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shen DaiDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA 70433, USA.
Fengming LiuDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA 70433, USA.
Zhongnan QinKey Laboratory of Cardiovascular and Cerebrovascular Medicine, Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Jinyan ZhangDepartment of Hepatobiliary and pancreatic surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Jiayi ChenDepartment of Clinical Laboratory Department, Shanghai Tenth People's Hospital of Tongji University, Shanghai 200072, China.
Wen-Xing DingDepartment of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas 66160, USA; 8Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.
Dechun FengLaboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.
Yong JiKey Laboratory of Cardiovascular and Cerebrovascular Medicine, Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Xuebin QinDivision of Comparative Pathology, Tulane National Primate Research Center, Covington, LA 70433, USA.
Tulane University · USNational Institute on Alcohol Abuse and Alcoholism · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCapillary PermeabilityCell CommunicationChemokine CXCL10Concanavalin ADisease Models, AnimalEndothelial CellsEndothelium, VascularHepatitisHepatitis CHumansKupffer CellsLiverLiver CirrhosisLiver TransplantationMiceChemokine CXCL10Concanavalin ACXCL10 protein, humanCxcl10 protein, mouseCell ablationCXCL10HepatitisKupffer cellsSinusoid endothelial cells

Identifiers

PMID32641985
PMCPMC7330839
OpenAlexW3035630981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.