Evidence map›Paper›PMID 32641874›Full record

ReviewIndian journal of clinical biochemistry : IJCB2020

Hydroxychloroquine and Covid-19: A Cellular and Molecular Biology Based Update.

Amit Pal, Anil Pawar, Kalyan Goswami, Praveen Sharma, Rajendra Prasad

Open access · bronzeAbstract readReview
In one paragraph

Review in Indian journal of clinical biochemistry : IJCB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

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  11. Can hydroxychloroquine be protective against COVID-19-associated thrombotic events ?Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Amit Pal *Department of Biochemistry, AIIMS, Kalyani, 741235 West Bengal India.
Anil Pawar *Department of Zoology, DAV University, Jalandhar, 144012 Punjab India.
Kalyan GoswamiDepartment of Biochemistry, AIIMS, Kalyani, 741235 West Bengal India.
Praveen SharmaDepartment of Biochemistry, AIIMS, Jodhpur, 342005 Rajasthan India.
Rajendra PrasadDepartment of Biochemistry, MM Institute of Medical Sciences and Research, Mullana, Ambala, 133207 Haryana India.ORCID 0000-0002-7104-9077
All India Institute of Medical Sciences Raipur · INAll India Institute of Medical Sciences Jodhpur · INDAV University · INInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the time for finding a definitive and safe cure as a vaccine for novel Corona Virus Disease 2019 (Covid-19) is still far, there is need to study in depth about the other potential drugs, which can save millions of lives due to Covid-19 pandemic. Right at the center of the debate is the use of drug "Hydroxychloroquine" as a prophylaxis as well as a treatment strategy against Covid-19 in conjunction with azithromycin. In this review, we will study the cellular and molecular aspects of hydroxychloroquine, which had driven its use in Covid-19 patients, as well as its chemistry and pharmacokinetics along with clinical trials going on worldwide using hydroxychloroquine against Covid-19.

Indexed as

Covid-19Cytokine stormHydroxychloroquineSevere acute respiratory syndrome coronavirus 2

Identifiers

PMID32641874
PMCPMC7286553
OpenAlexW3033874182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.