Evidence map›Paper›PMID 32641873›Full record

ReviewIndian journal of clinical biochemistry : IJCB2020

Inflammation, Immunity and Immunogenetics in COVID-19: A Narrative Review.

Malavika Lingeswaran, Taru Goyal, Raghumoy Ghosh, Smriti Suri, Prasenjit Mitra, Sanjeev Misra, Praveen Sharma

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Indian journal of clinical biochemistry : IJCB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05844215 (Role of MMP-9, TIMP-1 as Markers of Lung Imaging and Functional Abnormality of COVID-19), which is not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
1.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05844215 completednot on this mapstarted 2021, after this paper: background citation

Role of MMP-9, TIMP-1 as Markers of Lung Imaging and Functional Abnormality of COVID-19

Typeobservational_patient_registrySponsorUniversitas AirlanggaRan2021 to 2022Enrolled78ConditionsPulmonary Infection, COVID-19, Extracellular Matrix AlterationArmsMMP-9 and TIMP-1
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. "SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2023
    Article
  3. Article
  4. Review
  5. Glutamine-Driven Metabolic Adaptation to COVID-19 Infection.Indian journal of clinical biochemistry : IJCB · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Prophylactic effect of cutaneous leishmaniasis against COVID-19: a case-control field assessment.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Impact of COVID-19 on Clinical Biochemistry: Indian Scenario.Indian journal of clinical biochemistry : IJCB · 2021
    Article
  18. Role of arachidonic cascade in COVID-19 infection: A review.Prostaglandins & other lipid mediators · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Malavika LingeswaranDepartment of Biochemistry, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Taru GoyalDepartment of Biochemistry, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Raghumoy GhoshDepartment of Biochemistry, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Smriti SuriDepartment of Biochemistry, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Prasenjit MitraDepartment of Biochemistry, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.ORCID 0000-0003-4826-1587
Sanjeev MisraDepartment of Surgical Oncology, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
Praveen SharmaDepartment of Biochemistry, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel Coronavirus Disease 2019 (COVID-19), that began in Wuhan Province, China was labelled as an International Public Health Emergency on January 30, 2020 and later was declared a pandemic by the World Health Organisation (WHO) on March 11, 2020. The causative agent, SARS-CoV-2 was the third coronavirus responsible for causing major disease outbreaks in human population after Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) caused by SARS-CoV and MERS-CoV respectively. The patients of COVID-19 present with a clinical feature resembling mild form of viral pneumonia which in certain cases progress to a severe form characterised by adult respiratory distress syndrome (ARDS) and/or multiorgan failure leading to death. The transition from mild to severe form of COVID-19 is affected by a lot of factors like age, co-morbidities etc. In the absence of an absolute cure, it is essential to explore the molecular pathogenesis of the disease to identify people at risk of developing severity so that alternative treatment modalities may be planned. The aim of this review is to provide an update on the general characteristics of SARS-CoV-2 and highlight the inflammatory changes and immune dysregulation that may help in identification of molecular predictors of disease severity.

Indexed as

COVID-19Cytokine stormImmunityImmunogeneticsInflammation

Identifiers

PMID32641873
PMCPMC7275846
OpenAlexW3034173319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.