ArticleHypertension research : official journal of the Japanese Society of Hypertension2020
The association of blood pressure with physical frailty and cognitive function in community-dwelling septuagenarians, octogenarians, and nonagenarians: the SONIC study.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Frailty before chronic disease: multisystem physiological differences in middle-aged adults from the UK Biobank.GeroScience · 2026Article
- Association between systolic blood pressure trajectories and successful aging in middle-aged and elderly Chinese individuals: a longitudinal study.BMC public health · 2025Article
- Medication Use by Older Adults with Frailty: A Scoping Review.Pharmacy (Basel, Switzerland) · 2025Review
- Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Association between salt intake and blood pressure among community-dwelling older adults based on their physical frailty status.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Multidimensional insights about healthy aging from the cohort study for community-dwelling older adults: The SONIC study.Geriatrics & gerontology international · 2025Review
- Pulse pressure tells the story of sarcopenia.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Associations between Cognitive Impairment, Weight Status and Comorbid Conditions in Hospitalized Adults of 55 Years and Older in Guadeloupe.Healthcare (Basel, Switzerland) · 2024Article
- Genetically determined blood pressure, antihypertensive drug classes, and frailty: A Mendelian randomization study.Aging cell · 2024Article
- Association between trajectories of systolic blood pressure and frailty outcome in middle-aged and older adults.The journal of nutrition, health & aging · 2024Article
- Hypertension facilitates age-related diseases. ~ Is hypertension associated with a wide variety of diseases?~.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Longitudinal association of hypertension and dyslipidemia with cognitive function in community-dwelling older adults: the SONIC study.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Observational
- Treatment of hypertension and obstructive sleep apnea counteracts cognitive decline in common neurocognitive disorders in diagnosis-related patterns.Scientific reports · 2023Article
- Factors associated with weight loss by age among community-dwelling older people.BMC geriatrics · 2023Article
- Current topics of frailty in association with hypertension and other medical conditions.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Hypertension, the decline of activities of daily living (ADL) and frailty.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Review
- Article
- Self-Monitoring Home Blood Pressure in Community-Dwelling Older People: Age Differences in White-Coat and Masked Phenomena and Related Factors-The SONIC Study.International journal of hypertension · 2022Article
- Blood pressure, frailty status, and all-cause mortality in elderly hypertensives; The Nambu Cohort Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- The relationship between blood pressure and cognitive function.International journal of cardiology. Cardiovascular risk and prevention · 2021Article
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Authors and funding
23 authors.
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Abstract
We investigated the association of systolic blood pressure (SBP) level with physical frailty and cognitive function in community-dwelling older Japanese. Using the 'Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians' survey as the baseline, we performed a cross-sectional analysis of people aged 70 ± 1 (n = 1000), 80 ± 1 (n = 978), and 90 ± 1 (n = 272) years. Medical histories and medications were collected via interviews conducted by medical professionals. Blood pressure (BP), grip strength, gait speed, and cognitive function were examined on site. Trend analysis and multiple regression analysis were used to determine the association of the SBP level with physical frailty and cognitive function. The principal finding was that the association of SBP with physical frailty and cognitive function varied depending on characteristics such as age, physical and cognitive function, and antihypertensive medication use. A lower SBP level was associated with a higher prevalence of physical frailty only among 80-year-olds who were on antihypertensive medication. A significant association was found between higher SBP and lower cognitive function among 70-year-olds, while among 90-year-olds, the opposite was found. No association was found among participants who were 80 years old or among participants of all ages without antihypertensive medication. Our finding that an inverted association between SBP and geriatric syndrome exists suggests that the treatment of older patients must be individualized to prevent geriatric syndrome.
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