ArticleNature2020
Microbiota modulate sympathetic neurons via a gut-brain circuit.
Erratum issuedAbstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 263 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
263citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
263 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Common auricular acupoint patterns for postoperative recovery across laparoscopic surgeries: a data mining-based systematic analysis.Frontiers in medicine · 2026Pooled it
- Neurotransmitter-mediated gut-brain axis: a bibliometric analysis of research trends and knowledge structure.Frontiers in microbiology · 2026Pooled it
- Article
- The OMMGut microbes · 2026Review
- Characterization and correlation of gut microbiota in major depressive disorder patients with suicidal ideation.BMC psychiatry · 2026Article
- Dynamic interaction between Escherichia coli enterotoxins and bacteriocins.The FEBS journal · 2026Article
- Microbial reactivation of host androgens directs enteric neuronal regulation of gut motility.Nature neuroscience · 2026Article
- A neurocutaneous NaScience advances · 2026Article
- From Iron to Depression: The Crosstalk Between the Periphery and Brain.Neuroscience bulletin · 2026Review
- Effect of Probiotic Supplementation in Older Individuals with Mild Cognitive Impairment and Alzheimer's Disease: A Randomized, Placebo-Controlled, Triple-Blind Clinical Trial.Probiotics and antimicrobial proteins · 2026Article
- Exercise mimetics: molecular mechanisms, biological and therapeutic effects.Molecular biomedicine · 2026Review
- Children with Autism Spectrum Disorder and Chronic Gastrointestinal Symptoms Have Alterations in Intestinal Neurotransmitter Pathways.Digestive diseases and sciences · 2026Article
- The gut microbiome shapes social behaviour across animal species.Nature reviews. Microbiology · 2026Review
- DSS Colitis Model: Traps, Tricks, and Reporting Recommendations.Biomedicines · 2026Review
- Protective effects of enteral acetate supplementation against brain injury in a rat model of necrotizing enterocolitis.Pediatric research · 2026Article
- The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents.The Journal of physiology · 2026Article
- Central control of gastrointestinal functions in health and disease.Physiological reviews · 2026Review
- Molecular mechanisms and therapeutic potential of tryptophan metabolism in gut-brain signaling transduction: a narrative review.Journal of neuroinflammation · 2026Review
- An image-based transcriptomics atlas reveals the regional and microbiota-dependent molecular, cellular, and spatial structure of the murine gut.Cell host & microbe · 2026Article
- Bisphenol S and Neurological Health: An Integrated Overview of Neurotoxicity and Underlying Mechanisms.Molecular neurobiology · 2026Review
203 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
18 authors.
Paul A MullerLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. pmuller@rockefeller.edu.ORCID http://orcid.org/0000-0002-1957-4763
Marc Schneeberger *Laboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Fanny Matheis *Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID http://orcid.org/0000-0001-9971-3315
Putianqi Wang *Laboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Zachary KernerLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Anoj IlangesLaboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Kyle PellegrinoLaboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Josefina Del MármolLaboratory of Neurophysiology and Behavior, The Rockefeller University, New York, NY, USA.
Tiago B R CastroLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.ORCID http://orcid.org/0000-0002-0359-0611
Munehiro FuruichiDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Matthew PerkinsFishberg Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Wenfei HanFishberg Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Arka RaoDonald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Amanda J PickardDonald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Justin R CrossDonald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kenya HondaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-8937-9835
Ivan de AraujoFishberg Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Daniel MucidaLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. mucida@rockefeller.edu.ORCID http://orcid.org/0000-0002-0000-0452
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MDeveloping, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6MResourceP40OD010996 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STRICK, PETER · 2012 to 2024
$11.0MINTESTINAL REGULATION OF ThPOK EXPRESSION AND CD4 HELPER T CELL FUNCTIONR01DK093674 · NIDDK · ROCKEFELLER UNIVERSITY · PI Daniel S Mucida · 2013 to 2026
$7.0MIntestinal surveillance by intraepithelial lymphocytesR01DK113375 · NIDDK · ROCKEFELLER UNIVERSITY · PI Semir Beyaz, Daniel S Mucida · 2017 to 2026
$5.5MNeuro-immune interactions at the intestinal surfaceR01DK126407 · NIDDK · ROCKEFELLER UNIVERSITY · PI Daniel S Mucida · 2020 to 2026
$3.9MFunctional mapping of enteric-associated neuronsR01DK116646 · NIDDK · ROCKEFELLER UNIVERSITY · PI MUCIDA, DANIEL S · 2017 to 2021
$2.1MUnderstanding how the thermogenic response is orchestrated in the central nervous systemK99DK120869 · NIDDK · ROCKEFELLER UNIVERSITY · PI SCHNEEBERGER, MARC · 2020 to 2021
$233kNCATS NIH HHS UL1 TR001866NCI NIH HHS P30 CA008748NIDDK NIH HHS K99 DK120869NIDDK NIH HHS R01 DK093674NIDDK NIH HHS R01 DK113375NIDDK NIH HHS R01 DK116646NIDDK NIH HHS R01 DK126407NIH HHS P40 OD010996
Abstract
Connections between the gut and brain monitor the intestinal tissue and its microbial and dietary content
Indexed as
AnimalsDysbiosisFemaleGanglia, SympatheticGastrointestinal MicrobiomeGastrointestinal MotilityGerm-Free LifeIntestinesMaleMiceMice, Inbred C57BLModels, AnimalNeural PathwaysNeuronsProto-Oncogene Proteins c-fosSympathetic Nervous SystemProto-Oncogene Proteins c-fos
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.