Evidence map›Paper›PMID 32641750›Full record

ReviewCommunications biology2020

Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer.

Dimple Chakravarty, Sujit S Nair, Nada Hammouda, Parita Ratnani, Yasmine Gharib, Vinayak Wagaskar, Nihal Mohamed, Dara Lundon, Zachary Dovey, Natasha Kyprianou and 1 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04761107 (Mitigating Risk of COVID-19 for Clinical Management of Genitourinary Diseases), which is not on this map. Cited by 95 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04761107 active not recruitingnot on this mapstarted 2021, after this paper: background citation

Mitigating Risk of COVID-19 for Clinical Management of Genitourinary Diseases

TypeobservationalSponsorIcahn School of Medicine at Mount SinaiRan2021 to 2026Enrolled15,240ConditionsCOVID-19 Infection, Genitourinary Cancer, Benign Urologic Conditions
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Dimple Chakravarty *Department of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. dimple.chakravarty@mountsinai.org.ORCID http://orcid.org/0000-0002-5021-4440
Sujit S Nair *Department of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. sujit.nair@mountsinai.org.ORCID http://orcid.org/0000-0002-3039-523X
Nada HammoudaDepartment of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Parita RatnaniDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Yasmine GharibDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0001-5440-3620
Vinayak WagaskarDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nihal MohamedDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Dara LundonDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Zachary DoveyDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Natasha KyprianouDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ashutosh K TewariDepartment of Urology and The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ash.tewari@mountsinai.org.ORCID http://orcid.org/0000-0002-3146-4524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent outbreak of infections and the pandemic caused by SARS-CoV-2 represent one of the most severe threats to human health in more than a century. Emerging data from the United States and elsewhere suggest that the disease is more severe in men. Knowledge gained, and lessons learned, from studies of the biological interactions and molecular links that may explain the reasons for the greater severity of disease in men, and specifically in the age group at risk for prostate cancer, will lead to better management of COVID-19 in prostate cancer patients. Such information will be indispensable in the current and post-pandemic scenarios.

Indexed as

BetacoronavirusPandemicsSex DistributionAngiotensin-Converting Enzyme 2Antineoplastic Agents, HormonalAntiviral AgentsComorbidityCoronavirus InfectionsCOVID-19Disease SusceptibilityDrug RepositioningFemaleForecastingGonadal Steroid HormonesHumansMaleACE2 protein, humanAngiotensin-Converting Enzyme 2Antineoplastic Agents, HormonalAntiviral AgentsGonadal Steroid HormonesNeoplasm ProteinsPeptidyl-Dipeptidase AProtease InhibitorsReceptors, VirusSerine EndopeptidasesTMPRSS2 protein, human

Identifiers

PMID32641750
PMCPMC7343823

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.