Evidence map›Paper›PMID 32641711›Full record

ArticleExperimental & molecular medicine2020

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy.

Nicolas Taveau, Aurélie Cubizolle, Laurent Guillou, Nicolas Pinquier, Espérance Moine, David Cia, Vasiliki Kalatzis, Joseph Vercauteren, Thierry Durand, Céline Crauste and 1 more

Open access · goldAbstract read
In one paragraph

Article in Experimental & molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nicolas Taveau *Institut des Neurosciences de Montpellier, INSERM U1051, F-34091, Montpellier, France.
Aurélie Cubizolle *Institut des Neurosciences de Montpellier, INSERM U1051, F-34091, Montpellier, France.
Laurent GuillouInstitut des Neurosciences de Montpellier, INSERM U1051, F-34091, Montpellier, France.
Nicolas PinquierInstitut des Neurosciences de Montpellier, INSERM U1051, F-34091, Montpellier, France.
Espérance MoineInstitut des Biomolecules Max Mousseron (IBMM), UMR 5247 - Université de Montpellier, CNRS, ENSCM, F-34095, Montpellier, France.
David CiaLaboratoire de Biophysique Neurosensorielle, UMR INSERM 1107, Facultés de Médecine et de Pharmacie, F-63001, Clermont-Ferrand, France.
Vasiliki KalatzisInstitut des Neurosciences de Montpellier, INSERM U1051, F-34091, Montpellier, France.
Joseph VercauterenInstitut des Biomolecules Max Mousseron (IBMM), UMR 5247 - Université de Montpellier, CNRS, ENSCM, F-34095, Montpellier, France.
Thierry DurandInstitut des Biomolecules Max Mousseron (IBMM), UMR 5247 - Université de Montpellier, CNRS, ENSCM, F-34095, Montpellier, France.
Céline Crauste *Institut des Biomolecules Max Mousseron (IBMM), UMR 5247 - Université de Montpellier, CNRS, ENSCM, F-34095, Montpellier, France.
Philippe Brabet *Institut des Neurosciences de Montpellier, INSERM U1051, F-34091, Montpellier, France. philippe.brabet@inserm.fr.ORCID http://orcid.org/0000-0003-2739-1622
Inserm · FRÉcole Nationale Supérieure de Chimie de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental light has deleterious effects on the outer retina in human retinopathies, such as ABCA4-related Stargardt's disease and dry age-related macular degeneration. These effects involve carbonyl and oxidative stress, which contribute to retinal cell death and vision loss. Here, we used an albino Abca4

Indexed as

LightAnimalscis-trans-IsomerasesDisease Models, AnimalDisease SusceptibilityDocosahexaenoic AcidsElectroretinographyKineticsMice, Inbred C57BLMice, KnockoutPhenolsPhloroglucinolRetinaRetinal DegenerationRetinal DiseasesRetinoid Isomerohydrolasecis-trans-IsomerasesDocosahexaenoic AcidsPhenolsPhloroglucinolRetinoid IsomerohydrolaseRetinoids

Identifiers

PMID32641711
PMCPMC8080701
OpenAlexW3038551195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.