Evidence map›Paper›PMID 32641681›Full record

ReviewCell death & disease2020

Is hydroxychloroquine beneficial for COVID-19 patients?

Xing Li, Ying Wang, Patrizia Agostinis, Arnold Rabson, Gerry Melino, Ernesto Carafoli, Yufang Shi, Erwei Sun

Abstract readReview
In one paragraph

Review in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Safety profile of COVID-19 drugs in a real clinical setting.European journal of clinical pharmacology · 2022
    Review
  10. Article
  11. Article
  12. Coronavirus Entry Inhibitors.Advances in experimental medicine and biology · 2022
    Article
  13. COVID-19 in patients with diabetes: factors associated with worse outcomes.Journal of diabetes and metabolic disorders · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xing LiDepartment of Rheumatology and Immunology, The Third Affiliated Hospital of Southern Medical University, No. 183, Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong, China.
Ying WangShanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, 200031, Shanghai, China.
Patrizia AgostinisVIB-KU Leuven Center for Cancer Biology, KU Leuven, Leuven, Belgium.
Arnold RabsonChild Health Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.
Gerry MelinoTOR, University of Rome Tor Vergata, 00133, Rome, Italy.ORCID http://orcid.org/0000-0001-9428-5972
Ernesto CarafoliVenetian Institute of Molecular Medicine, University of Padova, Rome, Italy.
Yufang ShiShanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, 200031, Shanghai, China. yfshi@suda.edu.cn.
Erwei SunDepartment of Rheumatology and Immunology, The Third Affiliated Hospital of Southern Medical University, No. 183, Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong, China. sunew@smu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019. As similar cases rapidly emerged around the world

Indexed as

Adenosine MonophosphateAlanineAnti-Inflammatory AgentsAntiviral AgentsBetacoronavirusChloroquineCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentCytokinesHumansHydroxychloroquinePandemicsPneumonia, ViralRiskSARS-CoV-2Adenosine MonophosphateAlanineAnti-Inflammatory AgentsAntiviral AgentsChloroquineCytokinesHydroxychloroquineremdesivir

Identifiers

PMID32641681
PMCPMC7341710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.