Evidence map›Paper›PMID 32641478›Full record

ArticleJournal of virology2020

PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection.

S Klein, D Ghersi, M P Manns, I Prinz, M Cornberg, A R M Kraft

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Individual Epitope-Specific CD8Pathogens (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

S KleinDepartment of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Hannover, Germany.
D GhersiSchool of Interdisciplinary Informatics, College of Information Science & Technology, University of Nebraska at Omaha, Omaha, Nebraska, USA.
M P MannsDepartment of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Hannover, Germany.
I PrinzCluster of Excellence Resolving Infection Susceptibility (RESIST: EXC), Hannover Medical School, Hannover, Germany.
M CornbergDepartment of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Hannover, Germany.
A R M KraftDepartment of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Hannover, Germany kraft.anke@mh-hannover.de.ORCID 0000-0002-9666-0753
Medizinische Hochschule Hannover · DEUniversity of Nebraska at Omaha · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Checkpoint inhibitors are effective in restoring exhausted CD8

Indexed as

AnimalsAntibodies, NeutralizingB7-H1 AntigenCD8-Positive T-LymphocytesCell ProliferationClonal AnergyClone CellsDisease Models, AnimalGene Expression RegulationHigh-Throughput Nucleotide SequencingHost-Pathogen InteractionsLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMaleMiceMice, Inbred C57BLAntibodies, NeutralizingB7-H1 AntigenCd274 protein, mouseNucleoproteinsReceptors, Antigen, T-Cellanti-PD-L1checkpoint inhibitorlymphocytic choriomeningitis virusnext-generation sequencing

Identifiers

PMID32641478
PMCPMC7459548
OpenAlexW3041753573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.