Evidence map›Paper›PMID 32641477›Full record

ArticleJournal of virology2020

Reconstitution of an RNA Virus Replicase in Artificial Giant Unilamellar Vesicles Supports Full Replication and Provides Protection for the Double-Stranded RNA Replication Intermediate.

Nikolay Kovalev, Judit Pogany, Peter D Nagy

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nikolay KovalevDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA.
Judit PoganyDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA.
Peter D NagyDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA pdnagy2@uky.edu.ORCID 0000-0003-4164-1237
University of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positive-strand RNA [(+)RNA] viruses are important pathogens of humans, animals, and plants and replicate inside host cells by coopting numerous host factors and subcellular membranes. To gain insights into the assembly of viral replicase complexes (VRCs) and dissect the roles of various lipids and coopted host factors, we have reconstituted

Indexed as

Biological AssayCell LineEndoplasmic ReticulumEndosomal Sorting Complexes Required for TransportErgosterolGene Expression RegulationHSP70 Heat-Shock ProteinsNicotianaPeptide Elongation FactorsPhosphatidylethanolaminesPhosphatidylinositol 3-KinasePhosphatidylinositol PhosphatesPhosphatidylserinesPlant CellsRecombinant ProteinsRibonuclease IIIEndosomal Sorting Complexes Required for TransportErgosterolHSP70 Heat-Shock ProteinsPeptide Elongation FactorsphosphatidylethanolaminePhosphatidylethanolaminesPhosphatidylinositol 3-Kinasephosphatidylinositol 3-phosphatePhosphatidylinositol PhosphatesPhosphatidylserinesRecombinant ProteinsRibonuclease IIIRNA-Dependent RNA PolymeraseRNA, Double-StrandedRNA, ViralUnilamellar LiposomesViral Proteinshost factorsin vitrophospholipidplantreplicationRNA virusTBSVtomato bushy stunt virus

Identifiers

PMID32641477
PMCPMC7459549
OpenAlexW3041282621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.