Evidence map›Paper›PMID 32641419›Full record

ArticleDisease models & mechanisms2020

Daughterless, the

Laura Tamberg, Mariliis Jaago, Kristi Säälik, Alex Sirp, Jürgen Tuvikene, Anastassia Shubina, Carl Sander Kiir, Kaja Nurm, Mari Sepp, Tõnis Timmusk and 1 more

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Laura TambergDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia laura.tamberg@taltech.ee mari.palgi@taltech.ee.
Mariliis JaagoDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.
Kristi SäälikDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.
Alex SirpDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.
Jürgen TuvikeneDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.
Anastassia ShubinaDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.ORCID 0000-0002-8132-5258
Carl Sander KiirDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.ORCID 0000-0002-0829-0482
Kaja NurmDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.
Mari SeppDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.ORCID 0000-0003-1733-8385
Tõnis TimmuskDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.
Mari PalgiDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia laura.tamberg@taltech.ee mari.palgi@taltech.ee.ORCID 0000-0001-6142-6142
Tallinn University of Technology · EE

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
NIH HHS P40 OD010949NIH HHS P40 OD018537
6 · The paper itself

Abstract

Mammalian transcription factor 4 (TCF4) has been linked to schizophrenia and intellectual disabilities, such as Pitt-Hopkins syndrome (PTHS). Here, we show that similarly to mammalian TCF4, fruit fly orthologue Daughterless (Da) is expressed widely in the

Indexed as

Association LearningBehavior, AnimalProteomeAnimalsAnimals, Genetically ModifiedBasic Helix-Loop-Helix ProteinsBrainDisease Models, AnimalDrosophila melanogasterDrosophila ProteinsFaciesGene Expression Regulation, DevelopmentalHEK293 CellsHumansHyperventilationIntellectual DisabilityBasic Helix-Loop-Helix ProteinsDa protein, Drosophiladlg1 protein, DrosophilaDrosophila ProteinsProteomeSynapsinsSyn protein, DrosophilaTumor Suppressor ProteinsAppetitive associative learningDaughterlessDrosophila melanogasterIntellectual disabilityNegative geotaxisPitt–Hopkins syndromeTCF4

Identifiers

PMID32641419
PMCPMC7406316
OpenAlexW3041052371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.