Evidence map›Paper›PMID 32641372›Full record

ArticleDiabetes care2020

Comparison of the FreeStyle Libre Pro Flash Continuous Glucose Monitoring (CGM) System and Point-of-Care Capillary Glucose Testing in Hospitalized Patients With Type 2 Diabetes Treated With Basal-Bolus Insulin Regimen.

Rodolfo J Galindo, Alexandra L Migdal, Georgia M Davis, Maria A Urrutia, Bonnie Albury, Cesar Zambrano, Priyathama Vellanki, Francisco J Pasquel, Maya Fayfman, Limin Peng and 1 more

2 registry-linked trialsOpen access · bronzeAbstract readComment
In one paragraph

Article in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 101 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 6 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05135676 nacompletednot on this mapstarted 2022, after this paper: background citation

Time in Glucose Hospital Target (TIGHT) - A Randomized Clinical Trial to Evaluate the Use of CGM to Achieve a Mean Glucose Target of 90 to 130 mg/dL Without Hypoglycemia in Hospitalized Adults With Type 2 Diabetes

TypeinterventionalSponsorJaeb Center for Health ResearchRan2022 to 2024Enrolled169ConditionsDiabetes Mellitus, Type 2ArmsBlinded CGM, real-time CGM
NCT06473480 narecruitingnot on this mapstarted 2024, after this paper: background citation

Continuous GLUCOse Monitoring System With a SENSor Compared to Fingerstick Glucose Monitoring in Surgical Wards (GLUCOSENS)

TypeinterventionalSponsorOdense University HospitalRan2024 to 2025Enrolled329ConditionsDiabetes Mellitus, Hypoglycemia (Diabetic), Hypoglycemia Night, HyperglycemiaArmsAbbott FreeStyle Libre System 2 Plus, Abbott Freestyle Libre Pro
3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 6 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. [Hospital diabetes management (Update 2026)].Wiener klinische Wochenschrift · 2026
    Guideline
  2. Pooled it
  3. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  4. Guideline
  5. Pooled it
  6. Guideline
  7. Trial
  8. Randomized Study Comparing Continuous Glucose Monitoring and Capillary Glucose Testing in Patients With Type 2 Diabetes After Hospital Discharge.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Trial
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Rodolfo J GalindoDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-9295-3225
Alexandra L MigdalDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-9295-3225
Georgia M DavisDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Maria A UrrutiaDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Bonnie AlburyDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Cesar ZambranoDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Priyathama VellankiDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.
Francisco J PasquelDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-3845-6703
Maya FayfmanDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-8733-3160
Limin PengRollins School of Public Health, Emory University, Atlanta, GA.ORCID 0000-0002-3845-6703
Guillermo E UmpierrezDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA geumpie@emory.edu.ORCID 0000-0002-3252-5026
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery PatientsK23GM128221 · NIGMS · EMORY UNIVERSITY · PI PASQUEL, FRANCISCO J · 2018 to 2022
$957k
Use of Continuous Glucose Monitoring (CGM) in End-Stage Renal Disease(ESRD) Patients with Type 2 DiabetesK23DK123384 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALINDO, RODOLFO · 2020 to 2024
$934k
Epigenetic Markers of Short- and Long- Term Near-Normoglycemia Remission in Patients with Ketosis-Prone DiabetesK23DK113241 · NIDDK · EMORY UNIVERSITY · PI VELLANKI, PRIYATHAMA · 2019 to 2021
$646k
NCATS NIH HHS UL1 TR002378NIDDK NIH HHS K23 DK113241NIDDK NIH HHS K23 DK123384NIDDK NIH HHS P30 DK111024NIGMS NIH HHS K23 GM128221
6 · The paper itself

Abstract

objectiveWe compared the performance of the FreeStyle Libre Pro continuous glucose monitoring (CGM) and point-of-care capillary glucose testing (POC) among insulin-treated hospitalized patients with type 2 diabetes (T2D). RESEARCH DESIGN AND

methodsThis was a prospective study in adult patients with T2D admitted to general medicine and surgery wards. Patients were monitored with POC before meals and bedtime and with CGM during the hospital stay. Study end points included differences between POC and CGM in mean daily blood glucose (BG), hypoglycemia <70 and <54 mg/dL, and nocturnal hypoglycemia. We also calculated the mean absolute relative difference (MARD), ±15%/15 mg/dL, ±20%/20 mg/dL, and ±30%/30 mg/dL and error grid analysis between matched glucose pairs.

resultsMean daily glucose was significantly higher by POC (188.9 ± 37.3 vs. 176.1 ± 46.9 mg/dL) with an estimated mean difference of 12.8 mg/dL (95% CI 8.3-17.2 mg/dL), and proportions of patients with glucose readings <70 mg/dL (14% vs. 56%) and <54 mg/dL (4.1% vs. 36%) detected by POC BG were significantly lower compared with CGM (all

conclusionsCompared with POC, FreeStyle Libre CGM showed lower mean daily glucose and higher detection of hypoglycemic events, particularly nocturnal and prolonged hypoglycemia in hospitalized patients with T2D. CGM's accuracy was lower in the hypoglycemic range.

Identifiers

PMID32641372
PMCPMC7809713
OpenAlexW3042208359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.