Evidence map›Paper›PMID 32641124›Full record

ArticleJournal of biomedical semantics2020

Enabling ad-hoc reuse of private data repositories through schema extraction.

Lars Christoph Gleim, Md Rezaul Karim, Lukas Zimmermann, Oliver Kohlbacher, Holger Stenzhorn, Stefan Decker, Oya Beyan

Abstract read
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Article in Journal of biomedical semantics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lars Christoph GleimInformatik 5, RWTH Aachen University, Ahornstr. 55, Aachen, 52062, Germany. gleim@cs.rwth-aachen.de.ORCID 0000-0002-3550-1847
Md Rezaul KarimInformatik 5, RWTH Aachen University, Ahornstr. 55, Aachen, 52062, Germany.
Lukas ZimmermannInstitute for Translational Bioinformatics, University Hospital Tübingen, Sand 14, Tübingen, 72076, Germany.
Oliver KohlbacherInstitute for Translational Bioinformatics, University Hospital Tübingen, Sand 14, Tübingen, 72076, Germany.
Holger StenzhornInstitute for Translational Bioinformatics, University Hospital Tübingen, Sand 14, Tübingen, 72076, Germany.
Stefan DeckerInformatik 5, RWTH Aachen University, Ahornstr. 55, Aachen, 52062, Germany.
Oya BeyanInformatik 5, RWTH Aachen University, Ahornstr. 55, Aachen, 52062, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSharing sensitive data across organizational boundaries is often significantly limited by legal and ethical restrictions. Regulations such as the EU General Data Protection Rules (GDPR) impose strict requirements concerning the protection of personal and privacy sensitive data. Therefore new approaches, such as the Personal Health Train initiative, are emerging to utilize data right in their original repositories, circumventing the need to transfer data.

resultsCircumventing limitations of previous systems, this paper proposes a configurable and automated schema extraction and publishing approach, which enables ad-hoc SPARQL query formulation against RDF triple stores without requiring direct access to the private data. The approach is compatible with existing Semantic Web-based technologies and allows for the subsequent execution of such queries in a safe setting under the data provider's control. Evaluation with four distinct datasets shows that a configurable amount of concise and task-relevant schema, closely describing the structure of the underlying data, was derived, enabling the schema introspection-assisted authoring of SPARQL queries.

conclusionsAutomatically extracting and publishing data schema can enable the introspection-assisted creation of data selection and integration queries. In conjunction with the presented system architecture, this approach can enable reuse of data from private repositories and in settings where agreeing upon a shared schema and encoding a priori is infeasible. As such, it could provide an important step towards reuse of data from previously inaccessible sources and thus towards the proliferation of data-driven methods in the biomedical domain.

Indexed as

Information Storage and RetrievalPrivacyComputer SecurityFeasibility StudiesInternetData accessDistributed systemsFAIR dataLinked dataPersonal health trainPrivacyQuery designRDFSchema extractionSemantic webSPARQL

Identifiers

PMID32641124
PMCPMC7341611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.